777885-07-1 Usage
General Description
(+/-)-4-benzyl-2-azetidinone, also known as N-benzyl-2-pyrrolidinone, is a chemical compound belonging to the class of azetidinones. It is a white crystalline solid that is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has a unique structure with a four-membered ring containing a nitrogen atom, which provides it with certain biological activities. (+/-)-4-benzyl-2-azetidinone has been studied for its potential applications in the development of new drugs, particularly in the field of central nervous system disorders and inflammation. Additionally, it has been utilized as a chiral building block in organic synthesis, making it a valuable compound for medicinal chemistry and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 777885-07-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,7,8,8 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 777885-07:
(8*7)+(7*7)+(6*7)+(5*8)+(4*8)+(3*5)+(2*0)+(1*7)=241
241 % 10 = 1
So 777885-07-1 is a valid CAS Registry Number.
777885-07-1Relevant articles and documents
Improved enzymatic syntheses of valuable β-arylalkyl-β-amino acid enantiomers
Tasnadi, Gabor,Forro, Enik,Fueloep, Ferenc
supporting information; experimental part, p. 793 - 799 (2010/06/20)
The enantioselective (E～ 200) Burkholderia cepacia-catalysed hydrolyses of β-amino esters with H2O (0.5 equiv.) in t-BuOMe or in i-Pr2O at 45 °C are described. The enantiomers of biologically relevant β-arylalkyl-substituted β-amino acids, and especially (R)-3-amino-3-(2,4,5-trifluorophenyl)butanoic acid, the intermediate of the new antidiabetic drug sitagliptine, were prepared with high enantiomeric excesses (ee≥96%) and in good yields (≥42%). The Royal Society of Chemistry 2010.
