77811-32-6Relevant articles and documents
Synthesis of Substituted Oxadiazolylindoles
Hiremath, Shivayogi P.,Goudar, Naganagouda N.,Purohit, Muralidhar G.
, p. 1031 - 1034 (2007/10/02)
Indole-3-carboxyhydrazides (2a-d) are prepared and reacted with triethyl orthoformate to yield 3-(1',3',4'-oxadiazol-2'-yl)indoles (4a1-d1). 2a-d on reaction with benzaldehyde yield the corresponding schiff bases (3a-c).These on oxidative cyclodehydrogenation give 3-(5'-phenyl-1',3',4'-oxadiazol-2'-yl)indoles (4a2-d2). 2a-d also react with CS2 to produce 3-(5'-thione-1',3',4'-oxadiazol-2'-yl)indoles (5a-c) which undergo Mannich reaction with formaldehyde and 2-aminothiazoles to yield 7a-d.