77868-77-0 Usage
Description
N-benzyl-2,4-dibromobutamide, also known as N-benzyl-2,4-dibromobutanamide, is a chemical compound characterized by the molecular formula C11H12Br2NO. It presents as a white to beige solid and has a molecular weight of 324.03 g/mol. N-benzyl-2,4-dibroMobutanaMide is frequently utilized in organic synthesis and chemical research, serving as a building block for the creation of other compounds. Additionally, it has been recognized for its medicinal properties and is under investigation for its potential as an anticonvulsant and antidyskinetic agent.
Uses
Used in Organic Synthesis:
N-benzyl-2,4-dibromobutamide is employed as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the formation of new chemical entities through reactions such as substitution, addition, and condensation, contributing to the development of novel pharmaceuticals and specialty chemicals.
Used in Chemical Research:
In the realm of chemical research, N-benzyl-2,4-dibromobutamide is used as a valuable building block for the exploration of new chemical reactions and mechanisms. Its reactivity and structural features make it an ideal candidate for studying reaction pathways and understanding the fundamental principles of organic chemistry.
Used in Pharmaceutical Development:
N-benzyl-2,4-dibromobutamide is used as a starting material in the development of new pharmaceuticals. Its potential medicinal properties have led to investigations into its use as an anticonvulsant, which could help in the treatment of epilepsy and other seizure disorders. Additionally, its potential as an antidyskinetic agent suggests it may be useful in managing movement disorders such as dystonia and chorea.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, N-benzyl-2,4-dibromobutamide is utilized for the design and synthesis of new drug candidates. Its unique structural features and reactivity make it a promising scaffold for the development of compounds with therapeutic potential, particularly in the areas of neurology and movement disorders.
Overall, N-benzyl-2,4-dibromobutamide is a versatile chemical compound with applications spanning across various industries, including organic synthesis, chemical research, pharmaceutical development, and medicinal chemistry. Its potential as a building block for new compounds and its medicinal properties make it a valuable asset in the ongoing pursuit of scientific advancements and therapeutic solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 77868-77-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,8,6 and 8 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77868-77:
(7*7)+(6*7)+(5*8)+(4*6)+(3*8)+(2*7)+(1*7)=200
200 % 10 = 0
So 77868-77-0 is a valid CAS Registry Number.
77868-77-0Relevant articles and documents
Reductive Alkylation of Tertiary Lactams via Addition of Organocopper (RCu) Reagents to Thioiminium Ions
Mateo, Pierre,Cinqualbre, Joséphine E.,Meyer Mojzes, Melinda,Schenk, Kurt,Renaud, Philippe
supporting information, p. 12318 - 12327 (2017/12/08)
A simple procedure for the conversion of tertiary lactams to 2-monoalkylated cyclic amines is described. The reaction sequence involves conversion of a lactam to a thioiminium ion followed by reaction with an organocopper (RCu) reagent and final reduction with triacetoxyborohydride. The reaction is high yielding and shows an excellent functional group tolerance. Its utility is demonstrated by a rapid synthesis of indolizidine 167B. The excellent chemoselectivity of the process, where only monoalkylation products are formed, is rationalized by a mechanism involving the formation of a transient enamine.
Chemoenzymatic enantioselective synthesis of 3-hydroxy-2-pyrrolidinones and 3-hydroxy-2-piperidinones
Kamal, Ahmed,Ramana, K. Venkata,Ramana, A. Venkata,Babu, A. Hari
, p. 2587 - 2594 (2007/10/03)
The enantioselective synthesis of 3-hydroxypyrrolidin-2-ones and 3-hydroxy piperidin-2-ones has been carried out in high enantiomeric excess employing immobilized lipase from Pseudomonas cepacia.
Synthesis of β-enaminoesters and lactams by Michael addition of N- benzylaniline to new allenic esters and lactams
Ibrahim-Ouali, Malika,Sinibaldi, Marie-Eve,Troin, Yves,Gardette, Daniel,Gramain, Jean-Claude
, p. 1827 - 1848 (2007/10/03)
The synthesis of original allenic lactams 2 and allenic esters 5 is presented and their Michael condensation with N-benzylaniline described.
