779344-40-0

Basic information

• Product Name: Pyrrolo[1,2-b]pyridazine-6-carboxamide, N-(2-aminophenyl)-3-cyano-5-methyl-4-[(4-phenoxyphenyl)amino]-
• CAS NO: 779344-40-0
• Molecular Formula: C28H22N6O2
• Molecular Weight: 474.522
• Mol File: 779344-40-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyrrolo[1,2-b]pyridazine-6-carboxamide, N-(2-aminophenyl)-3-cyano-5-methyl-4-[(4-phenoxyphenyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[1,2-b]pyridazine-6-carboxamide, N-(2-aminophenyl)-3-cyano-5-methyl-4-[(4-phenoxyphenyl)amino]-(779344-40-0)
• EPA Substance Registry System: Pyrrolo[1,2-b]pyridazine-6-carboxamide, N-(2-aminophenyl)-3-cyano-5-methyl-4-[(4-phenoxyphenyl)amino]-(779344-40-0)

Safety Data

• Hazardous Substances Data: 779344-40-0(Hazardous Substances Data)

Upstream product

• 427878-69-1 1-amino-3-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester 
• 612085-99-1 4-Chloro-3-cyano-5-methylpyrrolo[1,2-b]pyridazine-6-carboxylic acid ethyl ester 
• 612082-29-8 3-Cyano-5-methyl-4-[(4-phenoxyphenyl)amino]pyrrolo[1,2-b]pyridazine-6-carboxylic acid 
• 95-54-5 1,2-diamino-benzene 
• 5448-16-8 3-methyl-1H-pyrrole-2,4-dicarboxylic acid diethyl ester 
• 612083-24-6 3-Cyano-5-methyl-4-[(4-phenoxyphenyl)amino]pyrrolo[1,2-b]pyridazine-6-carboxylic acid ethyl ester 
• 612085-98-0 3-Cyano-1,4-dihydro-5-methyl-4-oxopyrrolo[1,2-b]pyridazine-6-carboxylic acid ethyl ester 

Relevant articles and documents

Pyrrolopyridazine MEK inhibitors

The synthesis and SAR of a series of pyrrolopyridazine MEK inhibitors are reported. Optimal activity was achieved by incorporation of a 4-phenoxyaniline substituent at C4 and an acylated amine at C6.