780-21-2

Basic information

• Product Name: N-benzylidene-4-chloroaniline
• Synonyms: N-benzylidene-4-chloroaniline;N-(4-Chlorophenyl)benzylideneamine;N-(4-Chlorophenyl)phenylmethanimine;N-Benzylidene-4-chlorobenzenamine;N-Benzylidene-p-chloroaniline;N-BENZYLIDENE-4-CHLOROANILINE, TECH.
• CAS NO: 780-21-2
• Molecular Formula: C₁₃H₁₀ClN
• Molecular Weight: 215.68
• Mol File: 780-21-2.mol
• Article Data: 200

Chemical Properties

• Boiling Point: 342.7 °C at 760 mmHg
• Flash Point: 161.1 °C
• Appearance: /
• Density: 1.08 g/cm³
• Vapor Pressure: 0.000146mmHg at 25°C
• Refractive Index: 1.567
• CAS DataBase Reference: N-benzylidene-4-chloroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzylidene-4-chloroaniline(780-21-2)
• EPA Substance Registry System: N-benzylidene-4-chloroaniline(780-21-2)

Safety Data

• Hazardous Substances Data: 780-21-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthesis, p. 967, 1985 DOI: 10.1055/s-1985-31406

InChI:InChI=1/C13H10ClN/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11/h1-10H/b15-10+

Upstream product

• 19865-58-8 N-(4-chlorophenyl)-α-phenylnitrone 
• 2948-37-0 N-(4-chlorophenyl)benzylamine 
• 34918-76-8 N-(4-chlorophenyl)benzimidoyl chloride 
• 3296-05-7 1-azido-4-chlorobenzene 
• 100-52-7 benzaldehyde 
• 106-47-8 4-chloro-aniline 
• 861308-74-9 N-(α-bromo-benzyl)-4-chloro-aniline 
• 100-00-5 4-chlorobenzonitrile 
• 100-51-6 benzyl alcohol 
• 6554-98-9 trans-4-Hydroxystilbene 
• 100-47-0 benzonitrile 
• 94-41-7 benzalacetophenone 
• 140-38-5 N-(4-chlorophenyl)urea 
• 79113-93-2 (±)-cis-3-phenoxy-1-(p-chlorophenyl)-4-phenyl-2-azetidinone 

Downstream Products

• 23575-74-8 diethyl {[(4-chlorophenyl)amino](phenyl)methyl}phosphonate 
• 72867-44-8 (N-benzoyl-4-chloro-anilino)-phenyl-acetonitrile 
• 101272-43-9 N-acetyl-p-chloroanilinophenylacetontrile 
• 102461-60-9 [α-(4-chloro-anilino)-benzyl]-malonic acid diethyl ester 
• 2948-37-0 N-(4-chlorophenyl)benzylamine 
• 96003-68-8 1,2-bis(4-chlorophenyl)-N¹,N²-diphenylethane-1,2-diamine 
• 34798-62-4 3-(4-chloro-phenyl)-5-phenoxymethyl-2-phenyl-oxazolidine 
• 69617-28-3 6-trans-styryl-3-(4-trans-styryl-phenyl)-benzo[d]isoxazole 
• 69600-14-2 5-methyl-3-(4-trans-styryl-phenyl)-benzo[d]isoxazole 
• 69600-20-0 6-chloro-3-(3-chloro-4-trans-styryl-phenyl)-benzo[d]isoxazole 
• 69591-89-5 3-(4-methoxy-phenyl)-6-trans-styryl-benzo[d]isoxazole 
• 69591-91-9 3-biphenyl-4-yl-6-trans-styryl-benzo[d]isoxazole 
• 38550-04-8 2-(4-styryl-phenyl)-2H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2,3]triazole 
• 69591-86-2 3-phenyl-6-trans-styryl-benzo[d]isoxazole 

Relevant articles and documents

Copper-Catalyzed Intramolecular Amination of C(sp3)-H Bond of Secondary Amines to Access Azacycles

The cross-coupling of C-N bond directly from inert C-H bonds is an ideal approach to synthesize saturated azacycles due to its high efficiency and atom economy. In this article, a copper-catalyzed intramolecular amination via the cross coupling of C(sp3)-H and N-H bonds of secondary amine has been reported, which exhibit excellent chemo- and regioselectivity, extensive substrate scope, and functional group tolerance in good to excellent yield, offering an efficient pathway to build nitrogen-containing heterocycle skeletons.

Sulfated polyborate: A dual catalyst for the reductive amination of aldehydes and ketones by NaBH4

An efficient, quick, and environment-friendly one-pot reductive amination of aldehydes or ketones was developed. In ethanol at 70 °C, a imination catalyzed by sulfated polyborate and further reduced by sodium borohydride yields various amines. The present method has many significant benefits, including a shorter reaction time, excellent yields, and a hassle-free, straightforward experimental process. The reaction has a wide range of applications due to its flexibility, including secondary amine for reductive amination.

Photocatalytic one-pot multidirectional N-alkylation over Pt/D-TiO2/Ti3C2: Ti3C2-based short-range directional charge transmission

Visible-light-induced one-pot, multistep, and chemoselectivity adjustable reactions highlight the economical, sustainable, and green process. Herein, we report Pt nanoparticles dispersed on S and N co-doped titanium dioxide/titanium carbide (MXene) (3%Pt/