78018-56-1

Basic information

• Product Name: (2-methyl-1,4-phenylene)bis(oxy)bis(tert-butyldimethylsilane)
• Synonyms: (2-methyl-1,4-phenylene)bis(oxy)bis(tert-butyldimethylsilane)
• CAS NO: 78018-56-1
• Molecular Weight: 352.665
• Mol File: 78018-56-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2-methyl-1,4-phenylene)bis(oxy)bis(tert-butyldimethylsilane)(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methyl-1,4-phenylene)bis(oxy)bis(tert-butyldimethylsilane)(78018-56-1)
• EPA Substance Registry System: (2-methyl-1,4-phenylene)bis(oxy)bis(tert-butyldimethylsilane)(78018-56-1)

Safety Data

• Hazardous Substances Data: 78018-56-1(Hazardous Substances Data)

Upstream product

• 95-71-6 2-methylbenzene-1,4-diol 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 583-69-7 2-bromobenzene-1,4-diol 
• 78018-59-4 1,4-Bis(tert-butyldimethysiloxy)-2-bromobenzene 
• 80-48-8 methyl p-toluene sulfonate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 1172113-63-1 (2-iodo-5-methyl-1,4-phenylene)bis(oxy)bis(tert-butyldimethylsilane) 
• 553-97-9 2-Methyl-1,4-benzoquinone 

Relevant articles and documents

Biomimetic synthesis of dimeric metabolite acremine g via a highly regioselective and stereoselective Diels-Alder reaction

The dimeric metabolite acremine G was synthesized featuring a highly regioselective and stereoselective Diels-Alder reaction between a TBS-protected hydroquinone diene and a structurally related alkenyl quinone. The major endo [4 + 2] adduct slowly transforms to acremine G by the atmospheric air under the deprotection conditions (in situ generated HF).

Pyridinium Chlorochromate Releases Quinones from Hydroquinone Silyl Ethers.

The pyridinium chlorochromate oxidation of six bis(trimethylsilyl) and six bis(tert-butyldimethylsilyl) ethers of p-hydroquinones at room temperature in methylene chloride solution gave the corresponding quinones in 60-90percent yield.The bis(trimethylsilyl) ethers were slightly more reactive than the bis(tert-butyldimethylsilyl) ethers.High oxidation efficiency was indicated by a 1:1 molar stoichiometry; however, more convenient reaction times were obtained at a 2:1 molar ratio of pyridinium chlorochromate (PCC) to hydroquinone silyl ether.The mechanism is discussed based upon comparisons of relative reaction rates with electrochemical oxidation potentials.