78033-18-8 Usage
Description
4,5-Diamino-3-isobutyl-1-methylpyrimidine-2,6-dione, with the CAS number 78033-18-8, is a chemical compound that is characterized by its yellow crystalline structure. It is primarily recognized for its utility in the field of organic synthesis, where it serves as a valuable building block for the creation of more complex molecules and compounds.
Uses
Used in Organic Synthesis:
4,5-Diamino-3-isobutyl-1-methylpyrimidine-2,6-dione is used as a synthetic building block for the development of various organic compounds. Its unique molecular structure, featuring both amino and isobutyl groups, allows it to be a versatile component in the synthesis of a wide range of molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4,5-Diamino-3-isobutyl-1-methylpyrimidine-2,6-dione is utilized as a key intermediate in the synthesis of therapeutic agents. Its incorporation into drug molecules can potentially enhance their pharmacological properties, such as potency, selectivity, and bioavailability, leading to the development of more effective treatments for various diseases and conditions.
Used in Agrochemical Industry:
4,5-Diamino-3-isobutyl-1-methylpyrimidine-2,6-dione also finds application in the agrochemical industry, where it is employed in the synthesis of active ingredients for pesticides and other crop protection products. Its use in this context can contribute to the development of more effective and environmentally friendly solutions for managing pests and diseases in agriculture.
Used in Dye and Pigment Industry:
4,5-DIAMINO-3-ISOBUTYL-1-METHYLPYRIMIDINE-2,6-DIONE's yellow crystalline nature makes it a potential candidate for use in the dye and pigment industry. It can be utilized in the development of new dyes and pigments with specific color properties, which can be applied in various industries, such as textiles, plastics, and printing inks.
Check Digit Verification of cas no
The CAS Registry Mumber 78033-18-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,0,3 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 78033-18:
(7*7)+(6*8)+(5*0)+(4*3)+(3*3)+(2*1)+(1*8)=128
128 % 10 = 8
So 78033-18-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H16N4O2/c1-5(2)4-13-7(11)6(10)8(14)12(3)9(13)15/h5H,4,10-11H2,1-3H3
78033-18-8Relevant articles and documents
Structure-activity relationships in a series of xanthine derivatives with antibronchoconstrictory and bronchodilatory activities
Merlos,Gomez,Vericat,Bartroli,Garcia-Rafanell,Forn
, p. 653 - 658 (2007/10/02)
Thirty-one 1,3,7,8-substituted xanthine derivatives have been synthesized and evaluated for bronchodilator and anti-bronchoconstrictory activities in in vitro tracheal relaxation and in vivo bronchospasm inhibition models. Activity tests have been complemented with phosphodiesterase inhibition and toxicological data. Structure-activity relationships are discussed. Compound 21 (1,3-diisobutyl-8-methylxanthine) has been selected for further pharmacological development because of its good activity profile and favourable therapeutic index, which is 14- and 38-fold greater than that of theophylline and IBMX, respectively.
Inhibition of separated forms of cyclic nucleotide phosphodiesterase from pig coronary arteries by 1,3-disubstituted and 1,3,8-trisubstituted xanthines
Wells,Garst,Kramer
, p. 954 - 958 (2007/10/02)
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