78073-50-4

Basic information

• Product Name: O-Phenoxymethyl-N,N-bis-trifluoromethyl-hydroxylamine
• CAS NO: 78073-50-4
• Molecular Weight: 275.15
• Mol File: 78073-50-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: O-Phenoxymethyl-N,N-bis-trifluoromethyl-hydroxylamine(CAS DataBase Reference)
• NIST Chemistry Reference: O-Phenoxymethyl-N,N-bis-trifluoromethyl-hydroxylamine(78073-50-4)
• EPA Substance Registry System: O-Phenoxymethyl-N,N-bis-trifluoromethyl-hydroxylamine(78073-50-4)

Safety Data

• Hazardous Substances Data: 78073-50-4(Hazardous Substances Data)

Upstream product

• 2154-71-4 bis-trifluoromethyl-aminooxyl 
• 100-66-3 methoxybenzene 

Relevant articles and documents

Nitroxide Chemistry. Part 18. Reaction of Bistrifluoromethyl Nitroxide with Some Ethers

Treatment of the methyl ethers MeOX (X = Me, Ph) with a stoicheiometric amount of bistrifluoromethyl nitroxide . = R.> at room temperature converts them efficiently into their bistrifluoromethylamino-oxymethyl counterparts, RCH2OX; the bis-derivative (RCH2)2O is a minor by-product in the case of dimethyl ether (X = Me).Multiple hydrogen-abstraction increases in importance with diethyl ether as substrate, the expected products RCHMeOEt and (RCHMe)2O being accompanied by a bis-derivative (RCH2CHROEt) arguably produced via the αβ-dehydrogenation 2R. + Et2O -> 2RH + CH2=CHOEt.The halogeno-ether MeOCF2CHFCl reacts slowly with the nitroxide at 50 deg C to yield a 7 : 1 mixture of the derivatives RCH2OCF2CHFCl and RCFClCF2OMe, hydrolysis of which gives the esters RCH2OCOCHFCl and RCFClCO2Me, respectively.The latter ester is best obtained via treatment of methyl chlorofluoroacetate with bistrifluoromethyl nitroxide.