780782-23-2

Basic information

• Product Name: (3R,4R,5R)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine
• Synonyms: (3R,4R,5R)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine
• CAS NO: 780782-23-2
• Molecular Weight: 453.654
• Mol File: 780782-23-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3R,4R,5R)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R,5R)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine(780782-23-2)
• EPA Substance Registry System: (3R,4R,5R)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4,5-epoxypiperidine(780782-23-2)

Safety Data

• Hazardous Substances Data: 780782-23-2(Hazardous Substances Data)

Upstream product

• 780782-28-7 tert-butyl (S)-3-hydroxy-3,6-dihydropyridine-1(2H)-carboxylate 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 169105-89-9 isofagomine 
• 858614-82-1 (3R,4R,5S)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-5-(hydroxymethyl)piperidine 
• 858614-84-3 (3R,4R,5S)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-5-(2-hydroxyethyl)piperidine 
• 780782-26-5 (3R,4R,5S)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-5-methylpiperidine 
• 780782-25-4 (3R,4R,5S)-N-tert-butoxycarbonyl-3-(tert-butyldiphenylsilyloxy)-4-hydroxy-5-vinylpiperidine 

Relevant articles and documents

A short and concise synthesis of isofagomine, homoisofagomine, and 5′-deoxyisofagomine

A short and concise synthesis of isofagomine derivatives via the epoxidation of chiral N-Boc-5-hydroxy-3-piperidene, followed by regioselective epoxide ring opening is described. This constitutes the first reported synthesis of homoisofagomine and the 5′-