78139-31-8

Basic information

• Product Name: 2-Benzylamino-2-(4-methoxy-phenyl)-acetamide
• Synonyms: 2-Benzylamino-2-(4-methoxy-phenyl)-acetamide
• CAS NO: 78139-31-8
• Molecular Weight: 270.331
• Mol File: 78139-31-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Benzylamino-2-(4-methoxy-phenyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzylamino-2-(4-methoxy-phenyl)-acetamide(78139-31-8)
• EPA Substance Registry System: 2-Benzylamino-2-(4-methoxy-phenyl)-acetamide(78139-31-8)

Safety Data

• Hazardous Substances Data: 78139-31-8(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 123-11-5 4-methoxy-benzaldehyde 
• 65551-44-2 2-(N-benzylamino)-2-(4-methoxyphenyl)acetonitrile 

Downstream Products

• 271583-25-6 benzylamino-(4-methoxy-phenyl)-acetic acid 
• 2540-53-6 2-(4-methoxyphenyl)glycine 
• 78139-40-9 3-hydroxy-4-p-methoxyphenyl-1,2,5-thiadiazole 

Relevant articles and documents

A facile synthesis of substituted phenylglycines

A convenient scaleable process for the preparation of substituted phenylglycines 2 by a modified Strecker reaction is described. Bisulfite- mediated addition of benzylamine and cyanide anion to substituted benzaldehydes 3 gave the aminonitriles 4 which were hydrolysed in two steps to the N-protected amino acid 1. Debenzylation using catalytic transfer hydrogenation gave the title compounds in good yield.