78148-21-7

Basic information

• Product Name: methyl (S)-2-acetamido-3-(3,4-dimethoxyphenyl)propanoate
• Synonyms: methyl (S)-2-acetamido-3-(3,4-dimethoxyphenyl)propanoate
• CAS NO: 78148-21-7
• Molecular Weight: 281.309
• Mol File: 78148-21-7.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: methyl (S)-2-acetamido-3-(3,4-dimethoxyphenyl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (S)-2-acetamido-3-(3,4-dimethoxyphenyl)propanoate(78148-21-7)
• EPA Substance Registry System: methyl (S)-2-acetamido-3-(3,4-dimethoxyphenyl)propanoate(78148-21-7)

Safety Data

• Hazardous Substances Data: 78148-21-7(Hazardous Substances Data)

Upstream product

• 72053-04-4 methyl 2-acetylamino-3-(3,4-dimethoxyphenyl)-2-propenoate 
• 39740-33-5 carboxymethyl-1 N-acetyl-2 (dihydroxy-3,4 phenyl)-3 alanine 
• 74-88-4 methyl iodide 
• 100719-08-2 α-Acetamino-β-(3,4-dimethoxy-phenyl)-acrylsaeure-methylester 
• 38879-47-9 (Z)-4-(3,4-dimethoxybenzylidene)-2-methyl-5(4H)-oxazolone 
• 78083-80-4 (S)-2-amino-3-(3,4-dimethoxyphenyl)propionic acid methyl ester 
• 108-24-7 acetic anhydride 

Downstream Products

• 523-02-4 (S)-(-)-norcoralydine 
• 6872-27-1 (R)-(+)-xylopinine 
• 78083-82-6 methyl 1,2,3,4-tetrahydro-6,7-dimethoxy-1-methylene-2-veratroylisoquinoline-3-carboxylate 

Relevant articles and documents

Easy access to drug building-blocks through benzylic C-H functionalization of phenolic ethers by photoredox catalysis

A visible light-mediated photocatalyzed C-C-bond forming method for the benzylic C-H functionalization of phenolether containing synthetic building blocks based on a radical-cation/deprotonation strategy is reported. This method allows the mild, selective generation of benzyl radicals in phenolic complex molecules and drug-like compounds, providing new entries in synthetic and medicinal chemistry.

Synthesis of new chiral amidophosphite ligands and their application in hydrogenation of benzodiazepinones and enamides

New chiral amidophosphites were synthesized and tested in the Ir-catalyzed hydrogenation of 4-substituted 1,3-dihydro-2H-1,5-benzodiazepin-2-ones and Rh-catalyzed hydrogenation of dehydro amino acid derivatives. The triphenylphosphine additive can considerably increase the enantioselectivity of both processes.

Practical enantioselective hydrogenation of α-aryl- and α-carboxyamidoethylenes by rhodium(I)-{1,2-bis[(o-tert-butoxyphenyl) (phenyl)phosphino]ethane}

The rhodium(I)-{1,2-bis[(o-tert-butoxyphenyl)(phenyl)phosphino]ethane} [Rh(I)-(t-Bu-SMS-Phos)] catalyst system displayed prime efficiency in the hydrogenation of large series of aamidostyrenes and a-amidoacrylates. Up to >99.9% enantiomeric excesses coupl