781650-32-6 Usage
Description
[(3R,6S)-6-(2,3-difluorophenyl)-2-oxoazepan-3-yl]carbaMate, also known as cariprazine, is a chemical compound that belongs to the class of antipsychotic medications. It is characterized by its ability to act as a dopamine D2 and D3 receptor partial agonist, as well as a serotonin 5-HT1A receptor partial agonist. This dual mechanism of action allows cariprazine to balance the levels of dopamine and serotonin in the brain, which can help alleviate symptoms associated with psychosis and mood disorders. Cariprazine is also known for its favorable safety profile and good tolerability, making it a valuable option for patients with schizophrenia and bipolar disorder.
Uses
Used in Pharmaceutical Industry:
Cariprazine is used as an antipsychotic medication for the treatment of schizophrenia and bipolar disorder. Its application is based on its ability to act as a partial agonist at dopamine D2 and D3 receptors, as well as a serotonin 5-HT1A receptor partial agonist. This dual mechanism of action helps to balance the levels of dopamine and serotonin in the brain, which can alleviate symptoms associated with these conditions.
Additionally, cariprazine's favorable safety profile and good tolerability make it an important option for patients with schizophrenia and bipolar disorder, providing a valuable alternative to other antipsychotic medications.
Check Digit Verification of cas no
The CAS Registry Mumber 781650-32-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,8,1,6,5 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 781650-32:
(8*7)+(7*8)+(6*1)+(5*6)+(4*5)+(3*0)+(2*3)+(1*2)=176
176 % 10 = 6
So 781650-32-6 is a valid CAS Registry Number.
InChI:InChI=1/C17H22F2N2O3/c1-17(2,3)24-16(23)21-13-8-7-10(9-20-15(13)22)11-5-4-6-12(18)14(11)19/h4-6,10,13H,7-9H2,1-3H3,(H,20,22)(H,21,23)/t10-,13-/m1/s1
781650-32-6Relevant articles and documents
CARBOXAMIDE HETEROCYCLIC CGRP RECEPTOR ANTAGONISTS
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, (2009/01/24)
Compounds of formula I: I wherein variables A1, A2, B, m, n, J, R4, G1, G2, G3 and Y are as described herein, which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as mi
Cgrp Receptor Antagonists
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Page/Page column 37, (2008/06/13)
Compounds of Formula I: and Formula II: (where variables R1, R2, R3, R4, A, B, D, G, J, Q, T, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or pr
CGRP RECEPTOR ANTAGONISTS
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Page/Page column 58, (2010/11/08)
Compounds of Formula (I) and Formula (II) (where variables R1, R2, R4, A, B, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache
