78186-91-1 Usage
Description
DiMethoxyphosphinylhydroxy Acetic Acid Methyl Ester is an organic compound with the molecular formula C4H10O6P. It is characterized by the presence of a phosphinyl group, a hydroxyl group, and a methyl ester group. This molecule is known for its unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
DiMethoxyphosphinylhydroxy Acetic Acid Methyl Ester is used as a pharmaceutical agent for its ability to release iron from the serum iron transport protein, transferrin. This property makes it a potential candidate for the treatment of conditions related to iron deficiency or dysregulation of iron metabolism.
Used in Biochemical Research:
In the field of biochemical research, DiMethoxyphosphinylhydroxy Acetic Acid Methyl Ester can be utilized as a research tool to study the role of iron in various biological processes and the mechanisms of iron transport and regulation. Its ability to affect the interaction between iron and transferrin can provide valuable insights into the molecular basis of iron-related diseases and the development of novel therapeutic strategies.
Used in Diagnostic Applications:
DiMethoxyphosphinylhydroxy Acetic Acid Methyl Ester may also find applications in the development of diagnostic tools and tests for assessing iron levels and transferrin function in patients. By understanding the compound's interaction with transferrin, researchers can potentially create new methods for detecting and monitoring iron-related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 78186-91-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,1,8 and 6 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 78186-91:
(7*7)+(6*8)+(5*1)+(4*8)+(3*6)+(2*9)+(1*1)=171
171 % 10 = 1
So 78186-91-1 is a valid CAS Registry Number.
78186-91-1Relevant articles and documents
Determination of absolute configuration of the phosphonic acid moiety of fosfazinomycins
Schiessl, Katharina,Roller, Alexander,Hammerschmidt, Friedrich
, p. 7420 - 7426 (2013/10/22)
Fosfazinomycins A and B produced by Streptomyces lavendofoliae share the same phosphonate moiety with one chiral centre of unknown configuration which was determined by synthesising both enantiomers of 2-hydroxy-2-phosphonoacetic acid methyl ester. A chiral cyclic phosphite was reacted with methyl glyoxylate in a Pudovik reaction to give a pair of diastereomeric α- hydroxyphosphonates, which were separated by HPLC. The configurations at C-2 were assigned on the basis of single crystal X-ray structure analysis. Deprotection of these diastereomers furnished the enantiomeric α-hydroxyphosphonic acids, of which the (S)-configured had the same sign of optical rotation as the phosphonic acid moiety of the two fosfazinomycins.
A CONVENIENT METHOD FOR THE SYNTHESIS OF Α-KETOESTERS FROM ALDEHYDES
Horne, David,Gaudino, John,Thompson, Wayne J.
, p. 3529 - 3532 (2007/10/02)
An efficient two step, two carbon homologation of aldehydes to α-ketoesters is described.
