78195-97-8

Basic information

• Product Name: Cyclopentanol, 1-(4-methylphenyl)-
• CAS NO: 78195-97-8
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• Mol File: 78195-97-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cyclopentanol, 1-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanol, 1-(4-methylphenyl)-(78195-97-8)
• EPA Substance Registry System: Cyclopentanol, 1-(4-methylphenyl)-(78195-97-8)

Safety Data

• Hazardous Substances Data: 78195-97-8(Hazardous Substances Data)

Upstream product

• 120-92-3 cyclopentanone 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 106-38-7 para-bromotoluene 

Downstream Products

• 833-85-2 5-(4-methylphenyl)-5-oxopentanoic acid 
• 945-96-0 4-methyl-ω-chlorovalerophenone 
• 29510-34-7 1-(1-Chloro-cyclopentyl)-4-methyl-benzene 
• 827-56-5 1-(4-tolyl)cyclopentene 

Relevant articles and documents

Terminal Trifluoromethylation of Ketones via Selective C-C Cleavage of Cycloalkanols Enabled by Hypervalent Iodine Reagents

We report the first terminal trifluoromethylation at aryl and alkyl ketones' ?, or more remote sites via the selective C-C bond cleavage of cycloalkanols. The noncovalent interactions between alcohols and hypervalent iodines(III) reagents were disclosed to activate both alcohols and the Togni I reagent in the dual photoredox/copper catalysis for the transformation. This reaction was scalable to the gram-scale synthesis, applicable to the structurally complex steroid trifluoromethylation, and extendable to the pentafluoroethylation.

New therapeutically active basic ethers. 1. 1-Arylcycloalkanol derivatives.

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