78242-20-3 Usage
Description
1-Methyl-1H-pyrazol-4-ol, also known as 1-Methyl-4-hydroxypyrazole, is a heterocyclic chemical compound with the molecular formula C4H6N2O. It belongs to the pyrazole class of chemicals and is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. Due to its versatile nature, it has potential applications in treating diseases such as cancer and neurodegenerative disorders, making it an important compound in chemical research and development.
Uses
Used in Pharmaceutical Industry:
1-Methyl-1H-pyrazol-4-ol is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
1-Methyl-1H-pyrazol-4-ol is used as a building block in the synthesis of agrochemicals, playing a role in the development of pesticides and other agricultural chemicals.
Used in Cancer Treatment Research:
1-Methyl-1H-pyrazol-4-ol is studied for its potential use in treating cancer, as it may contribute to the development of novel anticancer drugs.
Used in Neurodegenerative Disorder Treatment Research:
1-Methyl-1H-pyrazol-4-ol is also being investigated for its potential role in treating neurodegenerative disorders, with the aim of developing new therapeutic approaches for such conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 78242-20-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,2,4 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 78242-20:
(7*7)+(6*8)+(5*2)+(4*4)+(3*2)+(2*2)+(1*0)=133
133 % 10 = 3
So 78242-20-3 is a valid CAS Registry Number.
78242-20-3Relevant articles and documents
AMINOPYRAZINE COMPOUNDS AS HPK1 INHIBITOR AND THE USE THEREOF
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Page/Page column 94-95, (2021/02/26)
Disclosed herein is an aminopyrazine compound of Formula (I), or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, and pharmaceutical compositions comprising thereof. Also disclosed is a method of treating HPK1 related disorders or diseases by using the compound disclosed herein.
Cu(I)/sucrose-catalyzed hydroxylation of arenes in water: The dual role of sucrose
Murata, Shigeo,Takagi, Mio,Takita, Ryo,Watanabe, Ayako,Watanabe, Kohei
supporting information, p. 7827 - 7831 (2020/11/02)
A protocol for the hydroxylation of aryl halides catalyzed by copper(I) and sucrose in neat water has been developed. The dual role of sucrose, the reaction pathway, and the high selectivity for hydroxylation were investigated using a combination of experimental and theoretical techniques. This journal is
Regioselective palladium-catalyzed C–H arylation of 4-alkoxy and 4-thioalkyl pyrazoles
Vernier, William F.,Gomez, Laurent
supporting information, p. 4587 - 4590 (2017/11/15)
A methodology for the palladium-catalyzed regioselective C–H arylation of electron rich pyrazoles has been developed. New ligands and mild conditions (70–90 °C) have been identified for this transformation. An intramolecular application of the methodology provided a novel synthetic route for the regioselective synthesis of 1,5-dihydroisochromeno[4,3-c]pyrazoles and 1,5-dihydroisothiochromeno[4,3-c]pyrazoles.