78266-67-8Relevant articles and documents
Asymmetric approach towards the total synthesis of (+)-actinopyllic acid
Xue, Fei,Xiao, Tao,Li, Min,Zhang, Kai-Fang,He, Li-Ping,Qin, Yong,Liu, Xiao-Yu,Zhang, Dan
, p. 2109 - 2115 (2017)
This paper describes our efforts towards the asymmetric total synthesis of (+)-actinophyllic acid. Starting from the chiral oxazolidinone 9, an azocino [4,3-b]indolyl intermediate (5) possessing the A/B/C ring system and the C16 quaternary stereogenic center of actinophyllic acid has been synthesized. Key steps include a LHMDS-promoted condensation to establish the critical C2–C16 bond and a successive four-step transformation to assemble the eight-membered C-ring of the target molecule.
An Improved Preparation of 1-Hydroxyindole and the Synthesis of Some Related 3-Carboxylic Acids and 1-Methoxyindole-3-acetonitrile
Acheson, R. Morrin,Aldridge, Graham N.,Choi, Michael C. K.,Nwankwo, Joseph O.,Ruscoe, Margaret A.,Wallis, John D.
, p. 1301 - 1319 (2007/10/02)
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