78271-77-9

Basic information

• Product Name: 3-(4-bromophenyl)-2-methyl-3-oxopropanenitrile
• Synonyms: 3-(4-bromophenyl)-2-methyl-3-oxopropanenitrile
• CAS NO: 78271-77-9
• Molecular Weight: 238.084
• Mol File: 78271-77-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(4-bromophenyl)-2-methyl-3-oxopropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-bromophenyl)-2-methyl-3-oxopropanenitrile(78271-77-9)
• EPA Substance Registry System: 3-(4-bromophenyl)-2-methyl-3-oxopropanenitrile(78271-77-9)

Safety Data

• Hazardous Substances Data: 78271-77-9(Hazardous Substances Data)

Upstream product

• 4592-94-3 3-(4-bromophenyl)-3-oxopropanenitrile 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 107-12-0 propiononitrile 
• 99-73-0 para-bromophenacyl bromide 
• 6048-21-1 4-bromobenzoyl cyanide 
• 19481-82-4 2-bromopropionitrile 
• 141-52-6 sodium ethanolate 
• 74-88-4 methyl iodide 

Downstream Products

• 586-76-5 4-Bromobenzoic acid 

Relevant articles and documents

Indium-mediated coupling of bromoacetonitriles with aromatic acyl cyanides: convenient synthesis of aromatic α-cyano ketones

Indium-mediated coupling of bromoacetonitrile and 2-bromopropionitrile with a variety of aromatic acyl cyanides afforded the corresponding aromatic α-cyano ketones in moderate to good yields under mild and neutral conditions.

SUBSTITUTED 6-(1H-PYRAZOL-1-YL)PYRIMIDIN-4-AMINE DERIVATIVES AND USES THEREOF

The present invention covers substituted 6-(1H-pyrazol-1-yl)pyrimidin-4-amine compounds of general formula (I) as described and defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds, and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular and renal diseases, as a sole agent or in combination with other active ingredients.