78287-26-0 Usage
Description
7-METHYL CAMPTOTHECIN is a poorly water-soluble camptothecin analogue, which is a type of chemical compound derived from the Camptotheca tree. It is a yellow solid with significant potential in the field of cancer treatment due to its ability to act as a DNA topoisomerase I inhibitor.
Uses
Used in Pharmaceutical Industry:
7-METHYL CAMPTOTHECIN is used as an antitumor agent for its potential in cancer treatment. It functions as a DNA topoisomerase I inhibitor, which can help in the development of new camptothecin derivatives with improved efficacy and reduced side effects.
Used in Drug Design and Development:
7-METHYL CAMPTOTHECIN is used as a reference compound in the design and development of new camptothecin derivatives. Its properties and interactions with DNA topoisomerase I can provide valuable insights for creating more effective and targeted cancer treatments.
Used in QSAR Studies:
7-METHYL CAMPTOTHECIN is utilized in quantitative structure-activity relationship (QSAR) studies to understand the relationship between the chemical structure of camptothecin analogues and their biological activity as DNA topoisomerase I inhibitors. This information can be crucial for the development of more potent and selective anticancer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 78287-26-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,2,8 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 78287-26:
(7*7)+(6*8)+(5*2)+(4*8)+(3*7)+(2*2)+(1*6)=170
170 % 10 = 0
So 78287-26-0 is a valid CAS Registry Number.
78287-26-0Relevant articles and documents
Novel route for preparation of 7-methyl-camptothecin and its possible mechanism
Wang, Xin,Wen, Jiwu,Li, Gang,You, Tianpa
, p. 3163 - 3166 (2005)
A novel route for preparation of 7-methyl-camptothecin is described. Its possible mechanism is discussed. Copyright Taylor & Francis, Inc.
