78324-75-1 Usage
Description
3,4,5-Trifluorobenzamide is an organic compound that features a benzene ring with three fluorine atoms attached at the 3rd, 4th, and 5th positions, and an amide group attached to the nitrogen atom. It is known for its unique chemical properties and reactivity, which make it a valuable intermediate in the synthesis of various organic compounds.
Uses
Used in Pharmaceutical Industry:
3,4,5-Trifluorobenzamide is used as a key intermediate in the synthesis of N-(diphenylphosphoryl)benzamide derivatives, which are of significant interest in the pharmaceutical industry. These derivatives have potential applications as therapeutic agents, particularly in the development of new drugs targeting various diseases.
Used in Chemical Research:
3,4,5-Trifluorobenzamide is also used as a research compound in chemical laboratories. Its unique structure and reactivity make it a valuable tool for studying the effects of fluorination on the properties of organic molecules and for exploring new synthetic pathways and reactions.
Used in Material Science:
In the field of material science, 3,4,5-trifluorobenzamide can be utilized in the development of new materials with specific properties. Its fluorinated structure can contribute to the design of materials with enhanced stability, reactivity, or selectivity, which can be applied in various industrial processes or technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 78324-75-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,3,2 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 78324-75:
(7*7)+(6*8)+(5*3)+(4*2)+(3*4)+(2*7)+(1*5)=151
151 % 10 = 1
So 78324-75-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H4F3NO/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2H,(H2,11,12)
78324-75-1Relevant articles and documents
Stable and reusable nanoscale Fe2O3-catalyzed aerobic oxidation process for the selective synthesis of nitriles and primary amides
Murugesan, Kathiravan,Senthamarai, Thirusangumurugan,Sohail, Manzar,Sharif, Muhammad,Kalevaru, Narayana V.,Jagadeesh, Rajenahally V.
supporting information, p. 266 - 273 (2018/01/12)
The sustainable introduction of nitrogen moieties in the form of nitrile or amide groups in functionalized molecules is of fundamental interest because nitrogen-containing motifs are found in a large number of life science molecules, natural products and materials. Hence, the synthesis and functionalization of nitriles and amides from easily available starting materials using cost-effective catalysts and green reagents is highly desired. In this regard, herein we report the nanoscale iron oxide-catalyzed environmentally benign synthesis of nitriles and primary amides from aldehydes and aqueous ammonia in the presence of 1 bar O2 or air. Under mild reaction conditions, this iron-catalyzed aerobic oxidation process proceeds to synthesise functionalized and structurally diverse aromatic, aliphatic and heterocyclic nitriles. Additionally, applying this iron-based protocol, primary amides have also been prepared in a water medium.
