783324-30-1

Basic information

• Product Name: Spiro[cyclopropane-1,3(2H)-quinoline]-2,4(1H)-dione, 1-methyl- (9CI)
• Synonyms: Spiro[cyclopropane-1,3(2H)-quinoline]-2,4(1H)-dione, 1-methyl- (9CI)
• CAS NO: 783324-30-1
• Molecular Formula: C12H11NO2
• Molecular Weight: 201.22124
• Product Categories: METHYL
• Mol File: 783324-30-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Spiro[cyclopropane-1,3(2H)-quinoline]-2,4(1H)-dione, 1-methyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[cyclopropane-1,3(2H)-quinoline]-2,4(1H)-dione, 1-methyl- (9CI)(783324-30-1)
• EPA Substance Registry System: Spiro[cyclopropane-1,3(2H)-quinoline]-2,4(1H)-dione, 1-methyl- (9CI)(783324-30-1)

Safety Data

• Hazardous Substances Data: 783324-30-1(Hazardous Substances Data)

Upstream product

• 93574-03-9 4-hydroxy-3-(2-hydroxyethyl)-1-methyl-2(1H)-quinolinone 

Relevant articles and documents

Cyclization of 4-hydroxy-3-hydroxyalkylcarbostyrils under mitsunobu conditions

Reaction of 4-hydroxy-3-hydroxyalkyl-1-methyl-2(1H)quinolinones with Ph3P/DEAD gives either C- or O-cyclized products depending on chain length. Hydroxyethyl produces only spiro cyclopropylquinolinone 6, whereas hydroxypropyl affords only pyranoquinolinone 8. Hydroxybutyl gives a 2:1 mixture of spiro cyclopentylquinolinone 11 and oxepinoquinolinone 10.