78431-46-6 Usage
Description
(3S,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-pyridin-4-yl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline is a complex organic molecule characterized by a pyrazoloquinoline core structure. It features an acetyl group, a methoxy group, and a sulfonyl group attached to various positions of the core, which may contribute to its potential pharmaceutical and biological activities. (3S,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-pyridin-4-yl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline belongs to the class of pyrazolo[4,3-c]quinoline derivatives and warrants further investigation into its specific properties and possible applications through chemical and pharmacological research.
Uses
Used in Pharmaceutical Industry:
(3S,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-pyridin-4-yl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline is used as a potential therapeutic agent for [application reason] due to its unique molecular structure and the presence of functional groups that may interact with biological targets.
Used in Chemical Research:
In the field of chemical research, (3S,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-pyridin-4-yl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline serves as a subject for studying the synthesis, structural analysis, and potential modifications to its molecular framework. This can lead to the discovery of new compounds with improved or novel biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 78431-46-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,4,3 and 1 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 78431-46:
(7*7)+(6*8)+(5*4)+(4*3)+(3*1)+(2*4)+(1*6)=146
146 % 10 = 6
So 78431-46-6 is a valid CAS Registry Number.
78431-46-6Relevant articles and documents
Studies in Antifertility Agents: Part XXXII-Synthesis and Stereochemistry of 3,3a-trans- and cis-2(H)-Acetyl-3-aryl-3,3a-dihydropyrazolochromenes, Pyrazolobenzocycloalk-1-enes and 3,3a-trans- and cis-(2H)-Acetyl-3-aryl-8-methoxy-5-tosyl-3,3a,4,5-tetrahydropyrazolo<4,...
Sangwan, Naresh K.,Rastogi, Shri Nivas
, p. 135 - 139 (2007/10/02)
Condensation of 4-chromanones (1,2), benzocycloalkan-1-ones (3,4) and N-tosyl-6-methoxy-2,3-dihydro-4-quinolone (5) with araldehydes ( 6-9) in the presence of HCl, KOH and NaOMe respectively gives the corresponding arylideno-ketones (10-17).These arylidenes (10-17) when refluxed with NH2-NH2*H2O in AcOH furnish the title compounds, 3,3a-trans- and cis-2(H)-acetyl-3-aryl-3,3a-dihydropyrazolochromenes (18a,b-21a,b), pyrazolobenzocycloalk-1-enes (22a,b-23a,b), and 3,3a-trans- and cis-2(H)-acetyl-3-aryl-8-methoxy-5-tosyl-3,3a,4,5-tetrahydropyrazoloquinolines (24a,b-25a,b).This cis- and trans-isomers have been separated by column chromatography over silica gel or by fractional crystallization and their stereochemistry has been assigned on the basis of PMR decoupling studies.Refluxing of 3-benzylidene-4-chromanone (10) with PhNHNH2 furnishes 3,3a-trans-2,3-diphenyl-3,3a-dihydropyrazolochromene (26).Treatment of 4 with NH2NH2*H2O in AcOH affords its acethydrazone derivative (27).The trans- and cis-mixtures of compounds 24 and 25 show antiimplantation activity at 20 mg/kg dose in female albino rats.
