78443-72-8 Usage
Description
2,4-DICHLORO-6-HYDROXYBENZALDEHYDE is an organic compound characterized by its molecular structure featuring two chlorine atoms at the 2nd and 4th positions, a hydroxyl group at the 6th position, and an aldehyde group. It is a type of aromatic aldehyde with potential applications in various industries due to its chemical properties.
Uses
Used in Pharmaceutical Industry:
2,4-DICHLORO-6-HYDROXYBENZALDEHYDE is used as a key intermediate compound for the synthesis of various pharmaceuticals. Its unique structure allows it to be a building block for the development of new drugs with specific therapeutic properties.
Used in Chemical Synthesis:
In the field of organic chemistry, 2,4-DICHLORO-6-HYDROXYBENZALDEHYDE is used as a starting material for the synthesis of a range of chemical compounds, including dyes, pigments, and other specialty chemicals. Its reactivity and functional groups make it a versatile compound for creating diverse products.
Used in Antimicrobial Applications:
2,4-DICHLORO-6-HYDROXYBENZALDEHYDE is used as a precursor for the synthesis of indazole derivatives, which exhibit antibacterial activity. These derivatives can be utilized in the development of new antibiotics to combat drug-resistant bacterial strains.
Used in Inhibitor Development:
2,4-DICHLORO-6-HYDROXYBENZALDEHYDE is also used in the synthesis of compounds that act as inhibitors of DNA gyrase B, an enzyme involved in bacterial DNA replication. Inhibitors targeting this enzyme can potentially be used in the development of new antibacterial agents.
Check Digit Verification of cas no
The CAS Registry Mumber 78443-72-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,4,4 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 78443-72:
(7*7)+(6*8)+(5*4)+(4*4)+(3*3)+(2*7)+(1*2)=158
158 % 10 = 8
So 78443-72-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H4Cl2O2/c8-4-1-6(9)5(3-10)7(11)2-4/h1-3,11H
78443-72-8Relevant articles and documents
Pd-Catalyzed Ortho C-H Hydroxylation of Benzaldehydes Using a Transient Directing Group
Chen, Xiao-Yang,Ozturk, Seyma,Sorensen, Erik J.
supporting information, p. 6280 - 6283 (2017/12/08)
The direct Pd-catalyzed ortho C-H hydroxylation of benzaldehydes was achieved using 4-chloroanthranilic acid as the transient directing group, 1-fluoro-2,4,6-trimethylpyridnium triflate as the bystanding oxidant, and p-toluenesulfonic acid as the putative oxygen nucleophile. The unusual C-H chlorination and polyfluoroalkoxylation reactions signaled the importance of external nucleophiles to the outcome of Pd(IV) reductive eliminations.
Pyrazolopyrimidines as therapeutic agents
-
, (2008/06/13)
The present invention is directed to pyrazolopyrimidine derivatives of formula (I) wherein the substituents are defined herein, which are useful as kinase inhibitors and as such are useful for affecting angiogenesis and diseases and conditions associated with angiogenesis.
Pyrazolopyrimidines as therapeutic agents
-
, (2008/06/13)
The present invention provides compounds of Formula I, including pharmaceutically acceptable salts and/or prodrugs thereof, where G, R2, and R3 are defined as described herein.
