78478-66-7Relevant articles and documents
BIARYL AMIDES WITH MODIFIED SUGAR GROUPS FOR TREATMENT OF DISEASES ASSOCIATED WITH HEAT SHOCK PROTEIN PATHWAY
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Page/Page column 171; 180; 238-239, (2019/12/04)
Provided are biaryl amides and coumarin-based compounds with modified sugar groups for treatment of diseases associated with heat shock protein pathway. The compounds having the following formulas, wherein variables are as defined herein. Formulae (I), (II), (III), (IV), and (V), Pharmaceutical compositions of the compounds are also provided. These biaryl amides and coumarin-based derivatives with modified sugar groups are useful for treatment and prevention of diseases and disorders, including neurological disorders, such as neurodegenerative diseases and nerve damaging disorders, for example, diabetic peripheral neuropathy.
Novel cyclic tetraselenides of mannose: synthesis and mechanistic studies
Sivapriya, Kirubakaran,Suguna, Perumal,Chandrasekaran, Srinivasan
, p. 2091 - 2095 (2008/02/04)
In this Letter, we disclose the synthesis of novel cyclic tetraselenides starting from mannose which are very unusual and rare and have been synthesised for the first time. The structures are confirmed by X-ray analysis. The reactivity of the reagent tetr
Enantiomeric Synthesis of (+)-BCH-189 cytosine> from D-Mannose and Its Anti-HIV Activity
Chu, Chung K.,Beach, J. Warren,Jeong, Lak S.,Choi, Bo G.,Comer, Frank I.,et al.
, p. 6503 - 6505 (2007/10/02)
Enantiomerically pure (+)-BCH-189 has been synthesized from D-mannose via 1,6-thioanhydro-D-mannose and its anti-HIV activity has been determined in peripheral blood mononuclear cells.