78564-23-5

Basic information

• Product Name: 3-Pyridinecarbonitrile, 1,2-dihydro-6-methyl-4-phenyl-2-thioxo-
• Synonyms: 6-Methyl-4-phenyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile;4-phenyl-6-methyl-3-cyanopyridine-2<1H>thione
• CAS NO: 78564-23-5
• Molecular Formula: C13H10N2S
• Molecular Weight: 226.302
• Mol File: 78564-23-5.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: 3-Pyridinecarbonitrile, 1,2-dihydro-6-methyl-4-phenyl-2-thioxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarbonitrile, 1,2-dihydro-6-methyl-4-phenyl-2-thioxo-(78564-23-5)
• EPA Substance Registry System: 3-Pyridinecarbonitrile, 1,2-dihydro-6-methyl-4-phenyl-2-thioxo-(78564-23-5)

Safety Data

• Hazardous Substances Data: 78564-23-5(Hazardous Substances Data)

Upstream product

• 2700-22-3 Benzylidenemalononitrile 
• 1687-47-4 propane-2,2-dithiol 
• 7357-70-2 Cyanothioacetamide 
• 1817-57-8 4-phenyl-3-butyne-2-one 
• 72740-50-2 4-amino-6-phenyl-5-cyano-2-cyclohexanespiro-1,3-dithia-4-cyclohexene 
• 93-91-4 1-phenylbutan-1,3-dione 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 68029-52-7 (E)-2-cyano-3-phenylprop-2-enethioamide 
• 67-64-1 acetone 
• 95639-01-3 2,4,4-Tricyano-3-phenyl-but-3-enethioic acid amide 
• 102434-73-1 2,6-diamino-4-phenyl-3,5-dicyano-4H-thiopyran 
• 94639-04-0 6-Amino-2,2-dimethyl-4-phenyl-4H-[1,3]dithiine-5-carbonitrile 
• 100-52-7 benzaldehyde 
• 109-77-3 malononitrile 

Downstream Products

• 94638-98-9 3-Amino-6-methyl-4-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid amide 
• 78564-34-8 2-Ethylsulfanyl-6-methyl-4-phenyl-nicotinonitrile 
• 96517-70-3 (3-Cyano-6-methyl-4-phenyl-pyridin-2-ylsulfanyl)-acetic acid ethyl ester 
• 152068-90-1 Ni((C₆H₅)(CH₃)C₅HNS(CN))2 
• 128918-17-2 3-Amino-6-methyl-4-phenyl-thieno<2,3-b>pyridin-2-carbonsaeureamid 
• 150886-18-3 N-(2-Cyano-6-methyl-4-phenyl-thieno[2,3-b]pyridin-3-yl)-oxalamic acid ethyl ester 
• 118904-56-6 4-Methoxy-7-methyl-9-phenyl-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2-carboxylic acid methyl ester 
• 94638-94-5 3-Amino-6-methyl-4-phenyl-thieno[2,3-b]pyridine-2-carboxylic acid methyl ester 
• 94638-96-7 (3-amino-6-methyl-4-phenyl-thieno[2,3-b]pyridin-2-yl)-phenyl-methanone 
• 94638-95-6 3-Amino-6-methyl-4-phenyl-thieno<2,3-b>pyridin-2-carbonsaeureethylester 
• 94638-93-4 3-amino-6-methyl-2-phenyl-2-cyanothieno<2,3-b>pyridine 

Relevant articles and documents

Synthesis of 4,6-Disubstituted 2-Thioxo-1,2-dihydropyridine-3-carbonitriles by the Reaction of Acetylenic Ketones with Cyanothioacetamide

The reaction of acetylenic ketones with cyanothioacetamide in the presence of morpholine yields 4,6-disubstituted 2-thioxo-1,2-dihydropyridine-3-carbonitriles. Structure of the obtained compounds was proved using 2D NMR spectroscopy, as well as transformations into 3-aminothieno[2,3-b]pyridine-2-carboxamide derivatives.

Simple isomer separation of 4,6-disubstituted 2-thioxo-1,2-dihydro-pyridine-3-carbonitriles being formed in the reaction of asymmetrically substituted 1,3-diketones with cyanothioacetamide

-

RECYCLIZATION OF ENAMINE NITRILES DERIVED FROM 1,3-DITHIACYCLOHEX-4-ENE: NEW ROUTE TO THE STEREOSELECTIVE SYNTHESIS OF SUBSTITUTED 4,5-trans-1,4,5,6-TETRAHYDRO-2-PYRIDINETHIOLATES

-