78639-46-0

Basic information

• Product Name: Carbamic acid, [2-[(1-methylethyl)amino]-2-oxoethyl]-, phenylmethyl ester
• CAS NO: 78639-46-0
• Molecular Formula: C13H18N2O3
• Molecular Weight: 250.298
• Mol File: 78639-46-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-[(1-methylethyl)amino]-2-oxoethyl]-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-[(1-methylethyl)amino]-2-oxoethyl]-, phenylmethyl ester(78639-46-0)
• EPA Substance Registry System: Carbamic acid, [2-[(1-methylethyl)amino]-2-oxoethyl]-, phenylmethyl ester(78639-46-0)

Safety Data

• Hazardous Substances Data: 78639-46-0(Hazardous Substances Data)

Upstream product

• 98397-14-9 p-toluenesulphonic-Z-glycinic anhydride 
• 75-31-0 isopropylamine 
• 2899-60-7 Cbz-Gly-ONSuc 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 66866-43-1 N-(t-butoxycarbonyl)glycyl i-butyl carbonate 

Downstream Products

• 1403957-53-8 3-(N-(2-isopropylamino-2-oxoethyl)-N-sulfamoyl)benzamidinium trifluoroacetate 
• 1403957-52-7 3-(N-(2-isopropylamino-2-oxoethyl)-N-sulfamoyl)benzamidine 
• 1154326-09-6 2-(3-cyanophenylsulfonamido)-N-isopropylacetamide 
• 67863-05-2 2-amino-N-isopropylacetamide 

Relevant articles and documents

Palladium-catalyzed β-C-H arylation of aliphatic aldehydes and ketones using amino amide as a transient directing group

This paper describes a new amino-amide-based transient directing group (TDG). The TDG can exhibit better performance in the Pd-catalyzed arylation of aliphatic aldehydes and ketones. This reaction showed good substrate compatibility and regioselectivity. The results indicated that 3-amino-N-isopropylpropionamide was more beneficial to the β-arylation of aliphatic aldehydes than other TDGs under relatively mild conditions.

2-(1-OXO-1H-ISOQUINOLIN-2-YL)ACETAMIDE DERIVATIVES

Disclosed herein are 2-(1-oxo-1H-isoquinolin-2-yl)acetamide derivative of formula I, or pharmaceutically acceptable salts or solvates thereof wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions comprising 2-(1-oxo-1H-isoquinolin-2-yl)acetamide derivatives according to the present invention and their use in therapy.

2- (4-0X0-4H-QUINAZ0LIN-3-YL) ACETAMIDES AND THEIR USE AS VASOPRESSIN V3 ANTAGONISTS

The present invention relates to 2-(4-oxo4H-quinazolin-3-yl)acetamicle derivatives of formula (I), and to their use as vasopressin V3 antagonists, particularly for the treatment of depression.