78644-78-7

Basic information

• Product Name: N-(4-methoxyphenyl)pyridin-2-amine
• CAS NO: 78644-78-7
• Molecular Formula: C₁₂H₁₂N₂O
• Molecular Weight: 200.24
• Mol File: 78644-78-7.mol
• Article Data: 47

Chemical Properties

• Boiling Point: 340.2°Cat760mmHg
• Flash Point: 159.5°C
• Density: 1.159g/cm³
• CAS DataBase Reference: N-(4-methoxyphenyl)pyridin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-methoxyphenyl)pyridin-2-amine(78644-78-7)
• EPA Substance Registry System: N-(4-methoxyphenyl)pyridin-2-amine(78644-78-7)

Safety Data

• Hazardous Substances Data: 78644-78-7(Hazardous Substances Data)

Upstream product

• 15103-48-7 pyridine-2-sulfonic acid 
• 104-94-9 4-methoxy-aniline 
• 504-29-0 2-aminopyridine 
• 66107-29-7 4-methoxyphenyl triflate 
• 623-12-1 4-chloromethoxybenzene 
• 15009-91-3 2-nitropyridine 
• 5720-07-0 4-methoxyphenylboronic acid 
• 694-59-7 pyridine N-oxide 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 372-48-5 2-fluoropyridine 
• 696-62-8 para-iodoanisole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 5029-67-4 2-iodopyridine 
• 1150-26-1 N-(4-Methoxy-phenyl)-4-methyl-benzenesulfonamide 

Downstream Products

• 82564-29-2 4-(N-pyridin-2-ylamino)phenol 
• 1206970-13-9 N-(4-(3-chloropyrazin-2-yloxy)phenyl)pyridin-2-amine 
• 1231921-88-2 N-(4-((3-(4-morpholinyl)-2-pyrazinyl)oxy)phenyl)-2-pyridinamine 
• 123444-29-1 8-hydroxypyrido[1,2-a]benzimidazole 
• 1613148-88-1 N-(4-methoxy-2-nitrophenyl)pyridin-2-amine 
• 1383232-09-4 N-(4-methoxyphenyl)-N-methyl-2-aminopyridine 
• 1383231-76-2 N-methyl-N-(2-triisopropylsilylethynyl-4-methoxyphenyl)-2-aminopyridine 

Relevant articles and documents

In Situ Formation of Cationic π-Allylpalladium Precatalysts in Alcoholic Solvents: Application to C-N Bond Formation

We report an efficient Buchwald-Hartwig cross-coupling reaction in alcoholic solvent, in which a low catalyst loading showed excellent performance for coupling aryl halides (I, Br, and Cl) with a broad set of amines, amides, ureas, and carbamates under mild conditions. Mechanistically speaking, in a protic and polar medium, extremely bulky biarylphosphine ligands interact with the dimeric precatalyst [Pd(π-(R)-allyl)Cl]2 to form the corresponding cationic complexes [Pd(π-(R)-allyl)(L)]Cl in situ and spontaneously. The resulting precatalyst further evolves under basic conditions into the corresponding L-Pd(0) catalyst, which is commonly employed for cross-coupling reactions. This mechanistic study highlights the prominent role of alcoholic solvents for the formation of the active catalyst.

COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF

The present invention provides a novel compound capable of improving light emitting efficiency, stability and lifespan of an element, an organic electric element using the same, and an electronic device thereof.

Iridium(III)-Catalyzed Tandem Annulation of Pyridine-Substituted Anilines and α-Cl Ketones for Obtaining 2-Arylindoles

A facile and expeditious protocol for the synthesis of 2-arylindole compounds from readily available N-(2-pyridyl)anilines and commercially available α-Cl ketones through iridium-catalyzed C-H activation and cyclization is reported here. As a complementary approach to the conventional strategies for indole synthesis, the transformation exhibits powerful reactivity, tolerates a large number of functional groups, and proceeds with good to excellent yields under mild conditions, providing a straightforward method to obtain structurally diverse and valuable indole scaffolds. Furthermore, the reaction could be easily scaled up to gram scale.