78648-27-8 Usage
General Description
2-Pyrrolidin-1-yl-benzoic Acid, also known as tolmetin, is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation associated with conditions such as rheumatoid arthritis, osteoarthritis, and juvenile rheumatoid arthritis. It works by inhibiting the production of prostaglandins, which are chemicals in the body that cause pain, fever, and inflammation. Tolmetin is typically administered orally in the form of tablets or capsules, and is available by prescription only. It is important to use this medication as directed by a healthcare professional and to be aware of potential side effects, including stomach bleeding, kidney problems, and cardiovascular risks.
Check Digit Verification of cas no
The CAS Registry Mumber 78648-27-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,6,4 and 8 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 78648-27:
(7*7)+(6*8)+(5*6)+(4*4)+(3*8)+(2*2)+(1*7)=178
178 % 10 = 8
So 78648-27-8 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO2/c13-11(14)9-5-1-2-6-10(9)12-7-3-4-8-12/h1-2,5-6H,3-4,7-8H2,(H,13,14)
78648-27-8Relevant articles and documents
Direct access to anthranilic acid derivatives via CO2 incorporation reaction using arynes
Yoshida, Hiroto,Morishita, Takami,Ohshita, Joji
supporting information; scheme or table, p. 3845 - 3847 (2009/05/31)
(Chemical Equation Presented) CO2 was found to be directly convertible into anthranilic acid derivatives of great synthetic value through a three-component coupling using arynes and amines. Zwitterions arising from nucleophilic attack of amines to arynes serve as key intermediates in the coupling.
