786701-16-4Relevant articles and documents
Selectively guanidinylated derivatives of neamine. Syntheses and inhibition of anthrax lethal factor protease
Jiao, Guan-Sheng,Simo, Ondrej,Nagata, Melissa,O'Malley, Sean,Hemscheidt, Thomas,Cregar, Lynne,Millis, Sherri Z.,Goldman, Mark E.,Tang, Cho
, p. 5183 - 5189 (2006)
A series of mono-, di-, and tri-guanidinylated derivatives of neamine were prepared via selective guanidinylation of neamine. These molecules represent a novel scaffold as inhibitors of anthrax lethal factor zinc metalloprotease. Methods for the synthesis