78718-25-9 Usage
Description
Benexate hydrochloride, also known as Benexate HCl, is a cytoprotective agent primarily used in the treatment of ulcers. It functions by inhibiting the decrease of PGE2 and PGI2, which are prostaglandins that protect the gastrointestinal mucosa, induced by factors such as indomethacin or stress. Benexate hydrochloride is characterized by its relatively long duration of action, providing a significant advantage over other cytoprotective drugs in terms of efficacy and patient compliance.
Uses
Used in Pharmaceutical Industry:
Benexate hydrochloride is used as a therapeutic agent for the treatment of ulcers, particularly peptic ulcers, due to its ability to protect and repair the gastrointestinal mucosa. Its cytoprotective properties help in reducing the risk of ulcer formation and promoting healing.
Used in Gastroenterology:
In the field of gastroenterology, Benexate hydrochloride is used as a supportive treatment to manage gastrointestinal disorders and conditions that may lead to ulcers, such as gastritis, gastroesophageal reflux disease (GERD), and nonsteroidal anti-inflammatory drug (NSAID)-induced ulcers.
Brand Names:
Some of the brand names under which Benexate hydrochloride is marketed include Lonmiel and Ulgut. These formulations are available in various dosage forms, such as tablets and capsules, for oral administration.
Originator
Teikoku Chemical (Japan)
Check Digit Verification of cas no
The CAS Registry Mumber 78718-25-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,7,1 and 8 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 78718-25:
(7*7)+(6*8)+(5*7)+(4*1)+(3*8)+(2*2)+(1*5)=169
169 % 10 = 9
So 78718-25-9 is a valid CAS Registry Number.
InChI:InChI=1/C23H27N3O4.ClH/c24-23(25)26-14-16-10-12-18(13-11-16)21(27)30-20-9-5-4-8-19(20)22(28)29-15-17-6-2-1-3-7-17;/h1-9,16,18H,10-15H2,(H4,24,25,26);1H/t16-,18-;
