78747-28-1

Basic information

• Product Name: Cyclohexaneacetonitrile, -alpha--hydroxy--alpha--methyl-2-oxo-
• Synonyms: Cyclohexaneacetonitrile, -alpha--hydroxy--alpha--methyl-2-oxo-
• CAS NO: 78747-28-1
• Molecular Formula: C₉H₁₃NO₂
• Molecular Weight: 0
• Mol File: 78747-28-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclohexaneacetonitrile, -alpha--hydroxy--alpha--methyl-2-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexaneacetonitrile, -alpha--hydroxy--alpha--methyl-2-oxo-(78747-28-1)
• EPA Substance Registry System: Cyclohexaneacetonitrile, -alpha--hydroxy--alpha--methyl-2-oxo-(78747-28-1)

Safety Data

• Hazardous Substances Data: 78747-28-1(Hazardous Substances Data)

Upstream product

• 631-57-2 Acetyl cyanide 
• 6651-36-1 1-(Trimethylsilyloxy)cyclohexene 

Relevant articles and documents

Facile synthesis of a "ready to use" precursor of porphobilinogen and its amino acid derivatives

(Chemical Equation Presented) A practical synthesis of porphobilinogen based on the biosynthetic mechanism is described. The crossed Mukayiama aldol reaction is the key step creating the central carbon-carbon bond between the two protected forms of 5-aminolevulinic acids. The optimized sequence gives a crystalline, storable precursor, which can be transformed in high yield into porphobilinogen and bioconjugates thereof. The enzymatic hydrolysis of the precursor produces porphobilinogen in quantitative yield.