78756-98-6 Usage
General Description
Benzooxazol-2-yl-acetic acid is a chemical compound with the molecular formula C10H9NO3. It is a derivative of benzo[1,4]oxazin-3-one and is commonly used as a building block in the synthesis of various pharmaceuticals and agrochemicals. Benzooxazol-2-yl-acetic acid has been found to exhibit a range of biological activities, including anti-inflammatory and analgesic properties. It also has potential as a ligand for designing metal coordination complexes. This versatile compound is valuable in the field of medicinal chemistry and is a subject of ongoing research for its potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 78756-98-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,7,5 and 6 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 78756-98:
(7*7)+(6*8)+(5*7)+(4*5)+(3*6)+(2*9)+(1*8)=196
196 % 10 = 6
So 78756-98-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H7NO3/c11-9(12)5-8-10-6-3-1-2-4-7(6)13-8/h1-4H,5H2,(H,11,12)
78756-98-6Relevant articles and documents
An efficient synthesis of novel di-heterocyclic benzazole derivatives and evaluation of their antiproliferative activities
Algul, Oztekin,Ersan, Ronak Haj,Alagoz, Mehmet Abdullah,Duran, Nizami,Burmaoglu, Serdar
, p. 6926 - 6938 (2020/08/13)
A series of unsymmetrical nine di-heterocyclic compounds of benzazole derivatives were synthesized at one step via cyclization reaction. The compounds evaluated for in?vitro cytotoxic activity against A549, A498, HeLa, and HepG2 cancer cell lines. The biological evaluation results show that 23, 26 and 29 exhibit better activity against HepG2 and HeLa cancer cell lines. Compound 23 also showed good activity against A549, and A498 cancer cell lines. The analogs were further performed molecular docking studies against human cytochrome P450 2C8 monooxygenase enzyme, calculated some theoretical quantum parameters, ADMET descriptor and molecular electrostatic potential analysis. The strategy applied in this research work may act as a perspective for the rational design of potential anticancer drugs. Communicated by Ramaswamy H. Sarma.
