78775-33-4

Basic information

• Product Name: METHYL 5-CHLORO-2-METHOXY-4-METHYLAMINOBENZOATE
• Synonyms: METHYL 5-CHLORO-2-METHOXY-4-METHYLAMINOBENZOATE
• CAS NO: 78775-33-4
• Molecular Formula: C₁₀H₁₂ClNO₃
• Molecular Weight: 229.66
• Mol File: 78775-33-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: METHYL 5-CHLORO-2-METHOXY-4-METHYLAMINOBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 5-CHLORO-2-METHOXY-4-METHYLAMINOBENZOATE(78775-33-4)
• EPA Substance Registry System: METHYL 5-CHLORO-2-METHOXY-4-METHYLAMINOBENZOATE(78775-33-4)

Safety Data

• Hazardous Substances Data: 78775-33-4(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 20896-27-9 methyl 4-amino-5-chloro-2-methoxybenzoate 
• 78784-42-6 methyl 2-methoxy-4-(N-methyl-N-tosylamido)benzoate 
• 78775-32-3 methyl 5-chloro-2-methoxy-4-(N-methyl-N-tosylamido)benzoate 

Downstream Products

• 61694-98-2 5-chloro-2-methoxy-4-(methylamino)benzoic acid 
• 73328-60-6 N-(1-Benzyl-3-pyrrolidinyl)-5-chloro-2-methoxy-4-methylaminobenzamide 
• 78775-20-9 5-Chloro-N-(1-ethyl-pyrrolidin-3-yl)-2-methoxy-4-methylamino-benzamide 
• 78784-39-1 5-Chloro-N-(1-ethyl-5-phenyl-pyrrolidin-2-ylmethyl)-2-methoxy-4-methylamino-benzamide 
• 82689-91-6 N-[2-(Benzyl-methyl-amino)-ethyl]-5-chloro-2-methoxy-4-methylamino-benzamide 
• 70325-83-6 N-((2S,3R)-1-Benzyl-2-methyl-pyrrolidin-3-yl)-5-chloro-2-methoxy-4-methylamino-benzamide 
• 70325-83-6 Emilace 
• 82689-90-5 N-(1-Benzyl-pyrrolidin-2-ylmethyl)-5-chloro-2-methoxy-4-methylamino-benzamide 
• 78775-18-5 5-Chloro-N-(1-cyclohexyl-pyrrolidin-2-ylmethyl)-4-dimethylamino-2-methoxy-benzamide 

Relevant articles and documents

Isolation of a highly functionalized Troeger's base derivative via a novel reaction

Heating a solution of methyl 5-chloro-4-[(ethoxyoxoacetyl) amino]-2-methoxybenz-oate, 3 in DMSO gave rise to the formation of the highly substitute.

THERAPEUTIC AGENT FOR RESPIRATORY DISEASE CONTAINING 4-HYDROXYPIPERIDINE DERIVATIVE AS ACTIVE INGREDIENT

An agent for preventing/treating respiratory diseases contains, as an active ingredient, a compound represented by following Formula (I): wherein A is a group represented by L-W [wherein L is a bond or CH2; and W is O, SOn (wherein n is 0 to 2), or -NR7-(wherein R7 is hydrogen or lower alkyl)]; each of G1 and G2 is (CH2)r (wherein r is 0 to 2), provided that when n is 1, G1 and G2 may be bridged by lower alkylene; Y is a lower alkylene or (substituted) benzylidene; Z is a bond or O, provided that when Z is a bond, Y may form a 5- or 6-membered ring with carbon on the benzene ring; R1 is, for example, NO2, a lower alkoxycarbonyl, (substituted) carbamoyl, (protected) hydroxyl group, (protected) carboxyl, or (protected) N-hydroxycarbamoyl; each of R2and R3 is hydrogen, halogen, (halogenated) lower alkyl, (halogenated) lower alkoxy or NO2; each of R4 and R5 is, for example, hydrogen, halogen, (halogenated) lower alkyl, (halogenated) lower alkoxy, CN, or lower alkylsulfonyl; and R6 is hydrogen or lower alkyl, a salt thereof or a solvate of them. It has excellent antitussive activity when used as an agent for preventing/treating respiratory diseases such as lung cancer, common cold syndrome, pulmonary tuberculosis, pneumonia, acute bronchitis or chronic bronchitis.