78910-06-2

Basic information

• Product Name: 1H-1,2,3-Triazole, 1-ethyl-
• CAS NO: 78910-06-2
• Molecular Formula: C4H7N3
• Molecular Weight: 97.1197
• Mol File: 78910-06-2.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1H-1,2,3-Triazole, 1-ethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,3-Triazole, 1-ethyl-(78910-06-2)
• EPA Substance Registry System: 1H-1,2,3-Triazole, 1-ethyl-(78910-06-2)

Safety Data

• Hazardous Substances Data: 78910-06-2(Hazardous Substances Data)

Usage

Structure

Five-membered ring with three nitrogen atoms and two carbon atoms The compound has a unique structure that includes a five-membered ring with three nitrogen atoms and two carbon atoms, which contributes to its high reactivity and versatile applications.

Heterocyclic organic compound

Contains a ring structure with both carbon and nitrogen atoms 1-ethyl-1H-1,2,3-triazole is a heterocyclic compound, meaning it has a ring structure containing both carbon and nitrogen atoms, which gives it unique chemical properties.

Industrial applications

Pharmaceutical and agricultural industries This compound is widely used in the pharmaceutical and agricultural industries as a key building block in the synthesis of various biologically active compounds and agrochemicals.

Corrosion inhibitor

Protects materials from corrosion 1-ethyl-1H-1,2,3-triazole is used as a corrosion inhibitor, helping to protect materials from degradation caused by chemical or electrochemical reactions.

Flame retardant

Slows down or prevents the spread of fire The compound also serves as a flame retardant, which can slow down or prevent the spread of fire in various materials.

Potential applications

Materials science, bioconjugation, and click chemistry Due to its high reactivity and versatile molecular structure, 1-ethyl-1H-1,2,3-triazole has potential applications in the fields of materials science, bioconjugation, and click chemistry.

Environmental and health impacts

需谨慎考虑 While 1-ethyl-1H-1,2,3-triazole has many beneficial applications, its environmental and health impacts should be carefully considered, as with any chemical compound.

Upstream product

• 74-96-4 ethyl bromide 
• 288-36-8 1 ,2,3-Triazole 
• 288-36-8 1,2,3-triazole 
• 64-67-5 diethyl sulfate 
• 75-03-6 ethyl iodide 
• 13518-80-4 2-trimethylsilyl-2H-1,2,3-triazole 
• 78910-04-0 (2-hydroxymethyl)-1,2,3-triazole 

Relevant articles and documents

Two ways of spin crossover in an iron(ii) coordination polymer associated with conformational changes of a bridging ligand

1,4-Di(1-ethyl-1,2,3-triazol-5-yl)butane (bbtre) was prepared by lithiation of 1-ethyl-1,2,3-triazole, followed by alkylation with 1,4-dibromobutane. The ligand bbtre forms a three-dimensional network with Fe(ii), [Fe(bbtre)3](ClO4)2·2CH3CN, that exhibits thermally induced spin crossover (SCO). A change of temperature or change of spin state results in various types of structural transformation, leading to different structures that are stable in strictly defined temperature ranges. As a result, there are three spin crossover transitions arranged via two different paths. Thus, cooling below 280 K involves a HT(HS) → LT(HS) (HT, high temperature structure; LT, low temperature structure; HS, high spin) phase transition (PT), which is associated with conformational changes of the bbtre molecules and with deformation of the polymeric skeleton. In the LT phase incomplete and reversible LT(HS) ? LT(HS/LS) spin crossover occurs (LS, low spin). In contrast, rapid cooling (of a sample not previously thermally treated) allows the HT(HS) → LT(HS) phase transition to be avoided, and so complete HT(HS) → HT1(LS) SCO occurs. This means that the PT plays the role of a switch, which allows a choice of one of two ways in which the SCO will proceed. After rapid cooling, further heating to 150 K and subsequent cooling results in a reversible HT1(HS) ? HT1(LS) spin crossover (T↓1/2 = 130 K, T↑1/2 = 131 K). However, raising the temperature to 170-200 K leads to formation of a modulated structure HT2(HS) exhibiting the next reversible HT2(HS) ? HT2(LS) SCO (T↓1/2 = 121 K, T↑1/2 = 123 K). Finally, heating above 200 K involves the HT2(HS) → LT(HS) PT and results in a LT(HS) structure exhibiting incomplete LT(HS) ? LT(HS/LS) spin crossover.

THIAZOLE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS

A compound which is a thiazole derivative of Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, n, Z, L, Ring B, R4 and n are as herein defined. Such compounds are useful in the prevention and trea

General solution to the synthesis of N-2-substituted 1,2,3-triazoles

The regioselective N-alkylation of 1,2,3-triazoles 1 - 6 was studied. Good to excellent N-2 selectivity and high chemical yields for N-2-substituted 4,5-dibromotriazoles 7 were obtained with 4,5-dibromo- and 4-bromo-5- trimethylsilyl-1,2,3-triazoles. These building blocks can be readily converted to 2-mono-, 2,4-di-, and 2,4,5-polysubstituted triazoles 10 - 15, providing a general, protective, group-free method for the synthesis of N-2-substituted triazoles. Observed regioselectivities can be rationalized by a combination of Frontier Molecular Orbital, steric, and electrostatic directing effects on the heterocyclic scaffolds.