78979-49-4

Basic information

• Product Name: 4-Thiazolidinecarboxylic acid, 2-(4-nitrophenyl)-, ethyl ester
• CAS NO: 78979-49-4
• Molecular Formula: C12H14N2O4S
• Molecular Weight: 282.32
• Mol File: 78979-49-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Thiazolidinecarboxylic acid, 2-(4-nitrophenyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Thiazolidinecarboxylic acid, 2-(4-nitrophenyl)-, ethyl ester(78979-49-4)
• EPA Substance Registry System: 4-Thiazolidinecarboxylic acid, 2-(4-nitrophenyl)-, ethyl ester(78979-49-4)

Safety Data

• Hazardous Substances Data: 78979-49-4(Hazardous Substances Data)

Upstream product

• 3411-58-3 L-cystein ethyl ester 
• 555-16-8 4-nitrobenzaldehdye 
• 868-59-7 L-cysteine ethyl ester hydrochloride 

Downstream Products

• 642471-92-9 3-[N-(tert-butoxycarbonyl)-L-phenylalanyl]amino-3-ethoxycarbonyl-2,3-dihydrothiopheno[2,3-b]naphthalene-4,9-dione 
• 642471-93-0 3-[N-(tert-butoxycarbonyl)-D-phenylalanyl]amino-3-ethoxycarbonyl-2,3-dihydrothiopheno[2,3-b]naphthalene-4,9-dione 
• 368427-26-3 3-amino-3-(ethoxycarbonyl)-2,3-dihydrothieno[2,3-b]naphtho-4,9-dione 
• 78979-64-3 ethyl 2-(4-nitrophenyl)thiazole-4-carboxylate 
• 78979-56-3 (R)-3-Acetyl-2-(4-nitro-phenyl)-thiazolidine-4-carboxylic acid ethyl ester 

Relevant articles and documents

Reversible thiazolidine exchange: A new reaction suitable for dynamic combinatorial chemistry

New dynamic combinatorial libraries (DCLs) were generated using the reversible aminothiol exchange reaction of thiazolidines and aromatic aldehydes. The reaction proceeded in aqueous buffered media at pH 4 and room temperature to generate thermodynamically controlled mixtures of heterocycles. The synthesis of an enantiomerically pure thiazolidinyloxazolidine is also reported. The oxazolidine moiety could be exchanged in CH2Cl2 in the presence of catalytic p-TsOH.