78987-19-6

Basic information

• Product Name: 2-(2-methylphenyl)-4-phenylisoquinoline-1,3(2H,4H)-dione
• CAS NO: 78987-19-6
• Molecular Weight: 327.382
• Mol File: 78987-19-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-methylphenyl)-4-phenylisoquinoline-1,3(2H,4H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-methylphenyl)-4-phenylisoquinoline-1,3(2H,4H)-dione(78987-19-6)
• EPA Substance Registry System: 2-(2-methylphenyl)-4-phenylisoquinoline-1,3(2H,4H)-dione(78987-19-6)

Safety Data

• Hazardous Substances Data: 78987-19-6(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 22978-49-0 2-methyl-N-(2-methylphenyl)benzamide 
• 933-88-0 ortho-toluoyl chloride 
• 95-53-4 o-toluidine 

Relevant articles and documents

Lithiation of N-(2-Alkylphenyl)alkanamides and Related Compounds. A Modified Madelung Indole Synthesis

A modified Madelung synthesis for the conversion of N-(alkylphenyl)alkanamides and related compounds to indoles, benzindoles, and azindoles has been developed.This procedure consists of treating the amide with 2 or 3 equiv of n-butyllithium or lithium diisopropylamide in tetrahydrofuran at temperatures from -20 to +25 deg C.Several examples where products other than indoles were formed from the starting amide are also reported.