78987-46-9 Usage
Description
4'-Morpholinopropiophenone, with the molecular formula C11H15NO2, is a ketone derivative that serves as a crucial intermediate in the synthesis of pharmaceuticals and organic compounds. This chemical compound is recognized for its versatility in acting as a reagent in various organic reactions, such as the formation of amides and esters. Its role as a building block in the production of drugs and other fine chemicals highlights its importance and value in the field of organic chemistry.
Uses
Used in Pharmaceutical Industry:
4'-Morpholinopropiophenone is used as a key intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing ones.
Used in Organic Chemistry Research:
As a versatile reagent, 4'-Morpholinopropiophenone is utilized in the formation of amides and esters, playing a significant role in advancing organic chemistry research and the discovery of novel chemical reactions.
Used in Fine Chemicals Production:
4'-MORPHOLINOPROPIOPHENONE is employed as a building block in the production of fine chemicals, which are essential in various industries such as agriculture, fragrances, and specialty chemicals. Its use in this capacity highlights its importance in creating high-quality and specialized products.
Check Digit Verification of cas no
The CAS Registry Mumber 78987-46-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,9,8 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 78987-46:
(7*7)+(6*8)+(5*9)+(4*8)+(3*7)+(2*4)+(1*6)=209
209 % 10 = 9
So 78987-46-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H17NO2/c1-2-13(15)11-3-5-12(6-4-11)14-7-9-16-10-8-14/h3-6H,2,7-10H2,1H3
78987-46-9Relevant articles and documents
Silver-catalyzed intermolecular amination of fluoroarenes
Wang, Yu,Wei, Chenlong,Tang, Ruyun,Zhan, Haosheng,Lin, Jing,Liu, Zhenhua,Tao, Weihua,Fang, Zhongxue
supporting information, p. 6191 - 6194 (2018/09/10)
A novel highly selective Ag-catalyzed intermolecular amination of fluoroarenes has been developed. This transformation starts from readily available 4-carbonyl fluorobenzene and NaN3 or other nitrogen-source, via amination followed by C-F bond cleavage, thus affording the desired 4-carbonyl arylamine products under mild conditions. The reaction is accelerated using a small amount of water. This pathway is distinct from a previously reported radical amination reaction.
Ruthenium-catalyzed remote electronic activation of aromatic C-F bonds
Watson, Andrew J. A.,Atkinson, Benjamin N.,Maxwell, Aoife C.,Williams, Jonathan M. J.
supporting information, p. 734 - 740 (2013/04/10)
The tandem isomerization and nucleophilic aromatic substitution of allylic fluoro-substituted benzylic alcohols is described for the first time. In the presence of the ruthenium complex Ru(PPh3)3(CO)(H) 2, 1-(4-fluorophenyl)prop-2-en-1-ol is converted into the corresponding para-amino ketone or para-phenolic substituted ketone. Copyright
