79108-84-2

Basic information

• Product Name: 6-chloro-2-(2-hydroxyphenyl)benzoxazole
• Synonyms: 6-chloro-2-(2-hydroxyphenyl)benzoxazole
• CAS NO: 79108-84-2
• Molecular Weight: 245.665
• Mol File: 79108-84-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 6-chloro-2-(2-hydroxyphenyl)benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-2-(2-hydroxyphenyl)benzoxazole(79108-84-2)
• EPA Substance Registry System: 6-chloro-2-(2-hydroxyphenyl)benzoxazole(79108-84-2)

Safety Data

• Hazardous Substances Data: 79108-84-2(Hazardous Substances Data)

Upstream product

• 28443-50-7 2-amino-5-chlorophenol 
• 74405-07-5 4-chloro-2,2-dimethyl-2H-benzo[e][1,3]oxazine 
• 90-02-8 salicylaldehyde 
• 60288-05-3 7-chlorodibenzo[b,f ][1,4]oxazepine 
• 15952-20-2 6-chloro-2-phenylbenzo[d]oxazole 

Downstream Products

• 1451257-10-5 6-chloro-2-[2-(prop-2-yn-1-yloxy)phenyl]-1,3-benzoxazole 
• 1451257-05-8 2-[2-[(1-benzyl-1H-1,2,3-triazol-4-yl)methoxyl]phenyl]-6-chlorobenzoxazole 

Relevant articles and documents

Palladium catalyzed Csp2-H activation for direct aryl hydroxylation: The unprecedented role of 1,4-dioxane as a source of hydroxyl radicals

A novel strategy for direct aryl hydroxylation via Pd-catalysed Csp2-H activation through an unprecedented hydroxyl radical transfer from 1,4-dioxane, used as a solvent, is reported with bio relevant and sterically hindered heterocycles and various acyclic functionalities as versatile directing groups.

Phenylboronic acid catalyzed-cyanide promoted, one-pot synthesis of 2-(2-hydroxyphenyl)benzoxazole derivatives

A novel, one-pot, phenylboronic acid catalyzed, cyanide promoted synthesis of 2-(2-hydroxyphenyl)benzoxazoles from salicylaldehydes and o-aminophenols is described. The synthesis is characterized by mild conditions, short reaction times, and simple workup of crystalline, high purity products.