791626-57-8 Usage
General Description
6-Fluoroquinolin-2-amine, also known as 6-Fluoro-2-quinolineamine, is a chemical compound that belongs to the class of quinoline derivatives. It consists of a quinoline ring with a fluorine atom and an amino group at positions 6 and 2, respectively. 6-FLUOROQUINOLIN-2-AMINE has potential applications in the development of pharmaceuticals and agrochemicals, as well as in the field of organic synthesis. Its unique structure and properties make it a valuable building block in the synthesis of diverse bioactive compounds and functional materials. Moreover, 6-fluoroquinolin-2-amine has demonstrated biological activity and has been investigated for its potential as an antitumor and antimicrobial agent. Overall, this chemical compound offers promising opportunities for drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 791626-57-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,9,1,6,2 and 6 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 791626-57:
(8*7)+(7*9)+(6*1)+(5*6)+(4*2)+(3*6)+(2*5)+(1*7)=198
198 % 10 = 8
So 791626-57-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H7FN2/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-5H,(H2,11,12)
791626-57-8Relevant articles and documents
Solvent-Dependent Cyclization of 2-Alkynylanilines and ClCF2COONa for the Divergent Assembly of N-(Quinolin-2-yl)amides and Quinolin-2(1 H)-ones
Wang, Ya,Zhou, Yao,Ma, Xingxing,Song, Qiuling
, p. 5599 - 5604 (2021/08/01)
Herein, we present an expedient Cu-catalyzed [5 + 1] cyclization of 2-alkynylanilines and ClCF2COONa to divergent construction of N-(quinolin-2-yl)amides and quinolin-2(1H)-ones by regulating the reaction solvents. Notably, nitrile acts as a solvent and performs the Ritter reactions. ClCF2COONa is used as a C1 synthon in this transformation, which also represents the first example for utilization of ClCF2COONa as an efficient desiliconization reagent. The current protocol involves in situ generation of isocyanide, copper-activated alkyne, Ritter reaction and protonation.
QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR
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Page 169-170, (2008/06/13)
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to quinoline-derived amides that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
