79222-77-8

Basic information

• Product Name: ethyl 2-[6-phenyl-pyridazin-3(2H)-one-2-yl]-acetate
• Synonyms: ethyl 2-[6-phenyl-pyridazin-3(2H)-one-2-yl]-acetate
• CAS NO: 79222-77-8
• Molecular Weight: 258.277
• Mol File: 79222-77-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ethyl 2-[6-phenyl-pyridazin-3(2H)-one-2-yl]-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-[6-phenyl-pyridazin-3(2H)-one-2-yl]-acetate(79222-77-8)
• EPA Substance Registry System: ethyl 2-[6-phenyl-pyridazin-3(2H)-one-2-yl]-acetate(79222-77-8)

Safety Data

• Hazardous Substances Data: 79222-77-8(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 2166-31-6 6-phenylpyridazin-3(2H)-one 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 1456070-60-2 N'-(phenylmethylidene)-2-(6-phenyl-3-oxo-2H-pyridazin-2-yl)acetohydrazide 
• 1456070-61-3 N'-[(4-methylphenyl)methylidene]-2-(6-phenyl-3-oxo-2H-pyridazin-2-yl)acetohydrazide 
• 1456070-62-4 N'-[(4-chlorophenyl)methylidene]-2-(6-phenyl-3-oxo-2H-pyridazin-2-yl)acetohydrazide 
• 1456070-63-5 N'-[(4-methoxyphenyl)methylidene]-2-(6-phenyl-3-oxo-2H-pyridazin-2-yl)acetohydrazide 
• 1456070-64-6 N'-[(4-fluorophenyl)methylidene]-2-(6-phenyl-3-oxo-2H-pyridazin-2-yl)acetohydrazide 
• 63900-48-1 2-acetonyl-6-phenyl-3(2H)-pyridazinone 
• 346407-30-5 N₁-(4-amino-3-methyl-1-propyl-uracil-5-yl)-2-[6-phenyl-pyridazin-3(2H)-one-2-yl]-acetamide 
• 346407-20-3 N₁-(4-amino-1,3-dimethyl-uracil-5-yl)-2-[6-phenyl-pyridazin-3(2H)-one-2-yl]-acetamide 
• 100517-84-8 2-(6-phenyl-3-oxo-2H-pyridazin-2-yl)acetohydrazide 
• 91973-93-2 2-[6-phenyl-pyridazin-3(2H)-one-2-yl]-acetic acid 

Relevant articles and documents

Synthesis of some new 3(2H)-pyridazinone derivatives and evaluation of their analgesic-anti-inflammatory and antimicrobial activities

In this study, 15 new 3(2H)-pyridazinone derivatives carrying N'-(4-substitutedphenylmethylidene)acetohydrazide moiety on lactam nitrogen were synthesized and their chemical structures were confirmed by 1H-NMR, mass, and elemental analysis. Analgesic and anti-inflammatory activities of the synthesized compounds were evaluated in mice. Among the synthesized compounds, compound 11e exhibited the best analgesic and anti-inflammatory activities, without causing any gastric effect in stomachs of tested animals. Additionally, the synthesized compounds were screened for their antibacterial and antifungal activities against some pathogenic strains.

Phase-Transfer Catalyzed N-Alkylation of 3(2H)-Pyridazinones (3-Oxo-2,3-dihydropyridazines)

-