79249-40-4Relevant articles and documents
A containing methyl pyrazine structure of the hydrazone compound and its preparation method and application (by machine translation)
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, (2017/06/02)
The invention discloses a containing methyl pyrazine structure of the hydrazone compound and its preparation method and application. It to 5 - methyl O-nitroaniline and hydrazine hydrate to obtain compound 1; compound 1 with the role of the BMF prepared compound 2; compound 2 by the reaction of the compound with phosphorus oxychloride 3; compound 3 is obtained by the reaction with hydrazine hydrate compound 4; compound 4 with the substituted aldehyde compound by the reaction of the compound (I). Its raw material is simple and easy, simple preparation method, after treatment is convenient, high product yield, but the compound is has herbicidal activity, in particular against bentgrasses, has certain herbicidal effect, to provide the basis for a new pesticide research. (by machine translation)
A pyrazine structure containing methyl 1, 2, 4 - triazole derivative and its preparation method and application (by machine translation)
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Paragraph 0015; 0027, (2017/02/17)
The invention discloses a pyrazine structure containing methyl 1, 2, 4 - triazole derivative and its preparation method and application. For 4 - methyl O-nitroaniline with hydrazine hydrate to produce compound (II). With the MBF reaction, to obtain the product (III). The compound (III) POCl for3 To obtain the product (IV) chloride. Compound (IV) with hydrazine hydrate and offer to obtain the intermediate product (V). Compound (V) in order to POCl3 As the solvent, with the substituted acid compound the response results in the type (I) shown in methyl pyrazine structure containing 1, 2, 4 - triazole derivatives; its raw material is simple and easy, simple preparation method, after treatment is convenient, high product yield, but the compound is has herbicidal activity, in particular against bentgrasses have good herbicidal effect, to provide the basis for a new pesticide research. (by machine translation)
A Versatile New Synthesis of Quinolines and Related Fused Pyridines. Part 8. Conversion of Anilides into 3-Substituted Quinolines and into Quinoxalines
Meth-Cohn, Otto,Rhouati, Salah,Tarnowski, Brian,Robinson, Andrew
, p. 1537 - 1543 (2007/10/02)
Anilides (4) (ArNHCOCH2R) are readily converted into 2-chloro-3-R-quinolines (5) under Vilsmeier conditions and the 3-chloro-group may be removed with zinc and acetic acid yielding 3-substituted quinolines (7).When N-nitrosodialkylamines are used in place of dimethylformamide as the Vilsmeier agent, the anilides are converted into 2-chloroquinoxalines in low yields.Several by-products are formed and the mechanisms have been explored.Thus, the formation of ethyl N-arylcarbamate from the corresponding propionanilide is shown to involve an C->O alkyl migration related to a Wolff rearrangement, while N-arylformimidoyl dichloride (18), nitriles, and isocyanides are derived from C-C cleavage of the substituted side-chain.Variation of the acid chloride component of the Vilsmeier reagent or of the solvent was generally unproductive though use of phosphoryl bromide instead of the chloride caused conversion of anilides into bromoquinolines in low yields.