79276-58-7 Usage
Chemical structure
QP is a heterocyclic compound with a quinolinyl and pyrrolidinone functional group.
Building block
It is often used as a building block for various medicinal and pharmaceutical compounds.
Versatile reactivity
QP has versatile reactivity, making it suitable for use in the synthesis of different compounds.
Stability
The compound is known for its stability, which is an important factor in pharmaceutical applications.
Drug discovery and development
QP has been studied for its potential applications in drug discovery and development.
Asymmetric synthesis
It has been investigated as a ligand or catalyst in asymmetric synthesis, a key technique in the production of enantiomerically pure compounds.
Anticancer potential
QP has demonstrated potential as an anticancer agent in preclinical studies.
Anti-inflammatory potential
The compound has also shown promise as an anti-inflammatory agent in preclinical studies.
Pharmaceutical industry
QP is a promising candidate for further research and development in the pharmaceutical industry due to its various potential applications and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 79276-58-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,2,7 and 6 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 79276-58:
(7*7)+(6*9)+(5*2)+(4*7)+(3*6)+(2*5)+(1*8)=177
177 % 10 = 7
So 79276-58-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H12N2O/c16-12-7-3-9-15(12)11-6-1-4-10-5-2-8-14-13(10)11/h1-2,4-6,8H,3,7,9H2
79276-58-7Relevant articles and documents
Synthesis of functionalized 3-, 5-, 6- and 8-aminoquinolines via intermediate (3-pyrrolin-1-yl)- and (2-oxopyrrolidin-1-yl)quinolines and evaluation of their antiplasmodial and antifungal activity
Vandekerckhove, Stéphanie,Van Herreweghe, Sofie,Willems, Jasmine,Danneels, Barbara,Desmet, Tom,De Kock, Carmen,Smith, Peter J.,Chibale, Kelly,D'Hooghe, Matthias
, p. 91 - 102 (2015)
(3-Pyrrolin-1-yl)- and (2-oxopyrrolidin-1-yl)quinolines were prepared via cyclization of diallylaminoquinolines and 4-chloro-N-quinolinylbutanamides, respectively, as novel synthetic intermediates en route to N-functionalized 3-, 5-, 6- and 8-aminoquinolines with potential biological activity. (3-Pyrrolin-1-yl)quinolines were subjected to bromination reactions, and the reactivity of (2-oxopyrrolidin-1-yl)quinolines toward lithium aluminum hydride and methyllithium was assessed, providing an entry into a broad range of novel functionalized (pyrrolidin-1-yl)- and (hydroxyalkylamino)quinolines. Antiplasmodial evaluation of these novel quinolines and their functionalized derivatives revealed moderate micromolar potency against a chloroquine-sensitive strain of the malaria parasite Plasmodium falciparum, and the two most potent compounds also showed micromolar activity against a chloroquine-resistant strain of P. falciparum. Antifungal assessment of (hydroxyalkylamino)quinolines revealed three compounds with promising MIC values against Rhodotorula bogoriensis and one compound with potent activity against Aspergillus flavus.
