79281-00-8 Usage
Chemical class
propanoic acids
2-(3-fluoro-4-methoxyphenyl)propanoic acid belongs to the class of propanoic acids, which are a group of organic compounds.
2. Derivative of propanoic acid
It is a derivative of propanoic acid, meaning it has a modified structure based on the parent compound, propanoic acid.
3. Fluorine atom at the third position
The phenyl ring of 2-(3-fluoro-4-methoxyphenyl)propanoic acid has a fluorine atom attached at the third position, which influences its chemical properties and activity.
4. Methoxy group at the fourth position
A methoxy group (-OCH3) is attached to the fourth position of the phenyl ring, further modifying the compound's properties and effects.
5. Nonsteroidal anti-inflammatory drug (NSAID)
2-(3-fluoro-4-methoxyphenyl)propanoic acid is used as a nonsteroidal anti-inflammatory drug, which is a class of medications that reduce inflammation and pain.
6. Pain and inflammation reduction
The compound is commonly used to alleviate pain and inflammation, making it effective for treating conditions such as arthritis and menstrual cramps.
7. Inhibition of inflammatory chemicals
8. Potential applications in medicinal chemistry and drug discovery
The chemical structure of 2-(3-fluoro-4-methoxyphenyl)propanoic acid suggests that it may have other potential applications in the field of medicinal chemistry and drug discovery, beyond its current use as an NSAID.
Check Digit Verification of cas no
The CAS Registry Mumber 79281-00-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,2,8 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 79281-00:
(7*7)+(6*9)+(5*2)+(4*8)+(3*1)+(2*0)+(1*0)=148
148 % 10 = 8
So 79281-00-8 is a valid CAS Registry Number.
79281-00-8Relevant articles and documents
USE OF QSAR IN DESIGN OF ANTIINFLAMMATORY FLUORINATED ARYLALKANOIC ACIDS
Kuchar, Miroslav,Grimova, Jaroslava,Rejholec, Vaclav,Tomkova, Hana,Jelinkova, Magda,Holubek, Jiri
, p. 296 - 306 (2007/10/02)
A series of 3-fluoro-4-alkoxyphenylalkanoic acids III was synthetized and their antiinflammatory activity and fibrinolytic capacity was evaluated.The suitable fluorinated derivative with better pharmacological profile than 3-chloro-4-benzyloxyphenylacetic acid (benzofenac) was selected.Experimental, biological activities of acids III were compared with those calculated by introducing the physico-chemical parameters into the formerly derived regression equations.Good coincidence was found out, as well as similarity of the regression equations derived for the originalseries of acids extended by the acids III.Lipophilicity of the acids under study was evaluated by partition thin-layer chromatography; the values of log P of benzyloxy derivatives IIIc-IIIf were lower than tabulated values - probably due to the intramolecular hydrophobic interactions of aromatic nuclei.
