792907-43-8

Basic information

• Product Name: (R)-allylglycine ethyl ester
• Synonyms: (R)-allylglycine ethyl ester
• CAS NO: 792907-43-8
• Molecular Weight: 143.186
• Mol File: 792907-43-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-allylglycine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-allylglycine ethyl ester(792907-43-8)
• EPA Substance Registry System: (R)-allylglycine ethyl ester(792907-43-8)

Safety Data

• Hazardous Substances Data: 792907-43-8(Hazardous Substances Data)

Downstream Products

• 54594-06-8 D-allylglycine 

Relevant articles and documents

(3R)- AND (3S)-METHYLPIPERAZINE-2,5-DIONE DERIVATIVES AS USEFUL INTERMEDIATES IN THE ENANTIOSELECTIVE SYNTHESIS OF α-AMINO ESTERS

Treatment of (3S)-3-methylpiperazine-2,5-dione 1 with lithium hexamethyldisilazide (LHMDS) followed by alkylation with several alkyl bromides affords (3S,6S)-3-methyl-6-alkyl derivatives 3 (a-e) in d.e. greater than 98percent.The same reaction sequence carried out on the (3R)-derivative 2 leads to a diastereoisomeric mixture of (3R,6S)-4 (a-e) and (3R,6R)-5 (a-e), the ratio 5 : 4 depending on the alkylating reagent.The configuration at C-6 (of 3, 4 and 5) has been assigned on the basis of 1H-NMR spectroscopic data and conformational analysis performed by the MMPMI program.Cleavage of the heterocyclic ring of 3 (b, d) and 5 (b, d) leads to the corresponding (S)- and (R)-α-amino esters respectively.