794488-74-7

Basic information

• Product Name: (2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID
• Synonyms: ASINEX-REAG BAS 13259302;(2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID;2,6-DIMETHYL-1-PIPERIDINEACETIC ACID;OTAVA-BB 7020671376;(2,6-Dimethyl-1-piperidinyl)acetic acid
• CAS NO: 794488-74-7
• Molecular Formula: C9H17NO2
• Molecular Weight: 171.24
• Mol File: 794488-74-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 266.6±23.0 °C(Predicted)
• Appearance: /
• Density: 1.009±0.06 g/cm3(Predicted)
• PKA: 2.47±0.10(Predicted)
• CAS DataBase Reference: (2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID(794488-74-7)
• EPA Substance Registry System: (2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID(794488-74-7)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 794488-74-7(Hazardous Substances Data)

Usage

Description

(2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID is a chemical compound with the molecular formula C9H17NO2. It belongs to the class of organic compounds known as piperidinecarboxylic acids and derivatives. It is a derivative of piperidine, which is a heterocyclic amine. (2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID serves as an intermediate in the synthesis of pharmaceuticals and organic compounds.

Uses

Used in Pharmaceutical Industry:
(2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID is used as an intermediate in the synthesis of various pharmaceuticals for its potential role in creating antiviral and antibacterial agents. Its unique structure allows it to be a key component in developing new medications.
Used in Organic Compounds Synthesis:
In the field of organic synthesis, (2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID is used as a building block for creating a variety of organic compounds. Its versatility in chemical reactions makes it valuable for constructing complex molecules.
Used in Central Nervous System Disorders Treatment:
(2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID is used in the development of drugs for the treatment of central nervous system disorders. Its potential therapeutic properties are being explored for managing conditions that affect the brain and spinal cord.
Used in Chemical Research:
(2,6-DIMETHYL-PIPERIDIN-1-YL)-ACETIC ACID also has applications in chemical research, where it may be utilized to study the properties of heterocyclic amines and their derivatives, contributing to the advancement of chemical knowledge and technology.

Upstream product

• 79-08-3 bromoacetic acid 
• 504-03-0 2.6-dimethylpiperidine 

Relevant articles and documents

A triarylphosphine-trimethylpiperidine reagent for the one-step derivatization and enrichment of protein post-translational modifications and identification by mass spectrometry

We report a new reagent that is capable of both chemical derivatization and selective enrichment of azide-labeled PTM peptides for sensitive identification by mass spectrometry (MS). Facile sample recovery, enhanced ionization and fragmentation in MS of the enriched PTM peptides are achieved, which leads to the identification of 3293 O-GlcNAc peptides and the location of 1706 sites in HeLa cells and efficiently expands the current mapping scale.

Nitrogen-containing cyclic compounds as iminium ion sources for selected reaction monitoring detection of derivatized analytes

Liquid chromatography–tandem mass spectrometry is one of the most sensitive tools for determination of trace amounts of analytes in metabolomics and proteomics. The highest sensitivity is achieved in selected reaction monitoring detection, which involves fragmentation of the molecular ion between two levels of mass selection. However, fragmentation of some compounds is complicated. Detection sensitivity of such analytes may be increased by derivatizing them with a specific moiety fragmentation of which results in product ion of high abundance. In this work, we reveal the influence of iminium ions' structures on their stability by comparing six nitrogen-containing cyclic compounds as derivatization reagents for tandem mass spectrometric analysis of amino group-containing analyte. Commercially available starting materials (piperidine, 2,6-dimethylpiperidine, 1-methylpiperazine, morpholine, pyrrolidine and 1-cyanomethyl-3-methylimidazolium ionic liquid) were used for the synthesis of corresponding carboxylic acids which were further used for derivatization of the model analyte tryptamine. Liquid chromatographic–mass spectrometric analysis of differently derivatized tryptamine was performed for the evaluation of release and stability of corresponding iminium ions under collision-induced dissociation conditions. As a result, morpholine moiety was shown being the most promising iminium ion source among tested compounds. Possible sub-fragmentation pathways of investigated iminium ions were discussed, and the structures of secondary product ions were proposed.