79544-29-9

Basic information

• Product Name: 2-Fluoro-6-iodobenzonitrile
• Synonyms: 6-Fluoro-2-iodobenzonitrile;2-Fluoro-6-iodobenzonitrile, 97+%;2-FLUORO-6-IODOBENZONITRILE;2-lodo-6-Fluoro benzonitrile;2-Fluoro-6-iodobenzonitrile 98%;2-Fluoro-6-iodobenzonitrile98%;2-Cyano-3-fluoro-1-iodobenzene
• CAS NO: 79544-29-9
• Molecular Formula: C₇H₃FIN
• Molecular Weight: 247.01
• EINECS: 279-200-7
• Product Categories: C6 to C7;Cyanides/Nitriles;Nitrogen Compounds;Fluorine series;blocks;Carboxes;FluoroCompounds;Iodides;Aromatic Nitriles;Miscellaneous
• Mol File: 79544-29-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 49-53 °C(lit.)
• Boiling Point: 271.309 °C at 760 mmHg
• Flash Point: >230 °F
• Appearance: White/Crystals or Crystalline Powder
• Density: 1.982 g/cm³
• Vapor Pressure: 0.071mmHg at 25°C
• Refractive Index: 1.577
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Sensitive: Light Sensitive
• BRN: 4971873
• CAS DataBase Reference: 2-Fluoro-6-iodobenzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-6-iodobenzonitrile(79544-29-9)
• EPA Substance Registry System: 2-Fluoro-6-iodobenzonitrile(79544-29-9)

Safety Data

• Hazard Codes: Xn,T,Xi,F
• Statements: 20/21/22-36/37/38-15-10
• Safety Statements: 36/37-43-36-26-7/8
• RIDADR: 3276
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 79544-29-9(Hazardous Substances Data)

Usage

Description

2-Fluoro-6-iodobenzonitrile is an aryl fluorinated building block characterized by its white to light yellow crystal powder form. It is a key intermediate in the chemical synthesis of various compounds due to its unique structure and properties.

Uses

Used in Pharmaceutical Industry:
2-Fluoro-6-iodobenzonitrile is used as a key intermediate in the synthesis of pharmaceutical compounds for its ability to enhance the properties of the final product, such as increasing lipophilicity and metabolic stability.
Used in Agrochemical Industry:
2-Fluoro-6-iodobenzonitrile is used as a building block in the development of agrochemicals, contributing to the creation of more effective and targeted pesticides and herbicides.
Used in Material Science:
2-Fluoro-6-iodobenzonitrile is utilized in the synthesis of advanced materials, such as polymers and coatings, where its fluorinated nature can impart specific properties like increased durability and resistance to environmental factors.
Used in Research and Development:
2-Fluoro-6-iodobenzonitrile serves as a valuable research tool in the development of new chemical entities and the study of structure-activity relationships in various fields, including medicinal chemistry and materials science.

InChI:InChI:1S/C7H3FIN/c8-6-2-1-3-7(9)5(6)4-10/h1-3H

Upstream product

• 1897-52-5 2,6 difluorobenzonitrile 
• 77326-36-4 2-amino-6-fluorobenzonitrile 

Downstream Products

• 507239-89-6 2-iodo-6-(2-methyl-4-pyrrolidin-1-yl-quinolin-7-ylmethoxy)-benzonitrile 
• 796967-84-5 4-iodo-1-methyl-1H-indazol-3-ylamine 
• 599191-73-8 4-iodine-1H-indazol-3-ylamine 
• 872179-04-9 5-p-tolylethynylquinazoline-2,4-diamine 

Relevant articles and documents

Super acid catalysed sequential hydrolysis/cycloisomerization of o-(acetylenic)benzamides under microwave condition: Synthesis, antinociceptive and antiinflammatory activity of substituted isocoumarins

Synthesis of isocoumarins and related compounds via triflic acid promoted hydrolysis/cyclization sequence of 2-(alkynyl)benzamides under microwave condition was achieved. The substrate scope of the reaction was broad to include not only aromatic but also