79611-55-5

Basic information

• Product Name: 3-(4-CHLOROPHENYL)-1,1,1-TRIFLUORO-2-PROPANONE
• Synonyms: 3-(4-CHLOROPHENYL)-1,1,1-TRIFLUORO-2-PROPANONE;3-(4-Chlorophenyl)-1,1,1-trifluoropropan-2-one
• CAS NO: 79611-55-5
• Molecular Formula: C₉H₆ClF₃O
• Molecular Weight: 222.59
• Mol File: 79611-55-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 219.7°C at 760 mmHg
• Flash Point: 86.7°C
• Appearance: /
• Density: 1.355g/cm³
• Vapor Pressure: 0.117mmHg at 25°C
• Refractive Index: 1.469
• CAS DataBase Reference: 3-(4-CHLOROPHENYL)-1,1,1-TRIFLUORO-2-PROPANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-CHLOROPHENYL)-1,1,1-TRIFLUORO-2-PROPANONE(79611-55-5)
• EPA Substance Registry System: 3-(4-CHLOROPHENYL)-1,1,1-TRIFLUORO-2-PROPANONE(79611-55-5)

Safety Data

• Hazardous Substances Data: 79611-55-5(Hazardous Substances Data)

Usage

General Description

3-(4-chlorophenyl)-1,1,1-trifluoro-2-propanone is a synthetic chemical compound with the formula C9H6ClF3O. It is an organofluorine compound that contains a propyl group bonded to a ketone functional group and a 4-chlorophenyl ring. This chemical is commonly used as a starting material in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also utilized in research and development processes due to its unique chemical properties. The compound has a high level of reactivity and is known for its strong nucleophilic and electrophilic characteristics, making it a versatile intermediate for various chemical reactions. However, it is important to handle and store this chemical with caution due to its potential health hazards and environmental impacts.

InChI:InChI=1/C9H6ClF3O/c10-7-3-1-6(2-4-7)5-8(14)9(11,12)13/h1-4H,5H2

Upstream product

• 383-63-1 ethyl trifluoroacetate, 
• 874-72-6 4-chlorobenzylmagnesium chloride 
• 6332-83-8 2-(4-chlorophenyl)-1-phenylethanone 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 

Downstream Products

• 157735-88-1 3-(4-Chlorophenyl)-1,1,1-trifluorohex-5-en-2-one 
• 1602864-53-8 (3S,4R)-4-(4-bromophenyl)-3-(4-chlorophenyl)-1,1,1-trifluoro-5-nitropentan-2-one 
• 1148050-25-2 3-(4-chlorophenyl)-1,1,1-trifluoropropan-2-ol 
• 120428-45-7 2-amino-4-trifluoromethyl-5-(4-chlorophenyl)thiophene trifluoroacetic acid salt 
• 142154-88-9 4-(4-Chlorophenyl)-5-trifluoromethylpyrrole-3-carbonitrile 
• 171352-61-7 4-(4-chloro-phenyl)-5-trifluoromethyl-1H-pyrrole-2-carbonitrile 
• 157735-80-3 4-(4-chloro-phenyl)-5-trifluoromethyl-1H-pyrrole-2-carbaldehyde 
• 157735-89-2 3-(4-chloro-phenyl)-5,5,5-trifluoro-4-oxo-pentanal 
• 157735-81-4 3-(4-Chlorophenyl)-2-trifluoromethylpyrrole 
• 142154-87-8 3-(4-Chlorophenyl)-1,1,1-trifluoro-2-propanone oxime 

Relevant articles and documents

Highly efficient synthesis of chiral α-CF3 amines via Rh-catalyzed asymmetric hydrogenation

Highly enantioselective catalytic asymmetric hydrogenation of α-CF3-enamides has been achieved by employing rhodium-DuanPhos as the catalyst, which provides a readily accessible method for the synthesis of chiral trifluoromethylated amines. The reaction has a broad substrate scope; both aryl- and alkyl-substituted α-CF3-enamides worked smoothly and afford the corresponding chiral amines in high yields and excellent enantioselectivities (up to 99% ee).

Synthesis of trifluoromethyl alcohols from tert-butoxy-β-(trifluoromethyl)styrenes and trifluoromethylbenzyl ketones under the conditions of the Leuckart-Wallach reaction

A novel pathway towards trifluoromethylalcohols by an unexpected reaction of tert-butoxy-β-(trifluoromethyl)styrenes or corresponding trifluoromethylbenzyl ketones under the conditions of the Leuckart-Wallach reaction was elaborated.

Bis- and tris(trifluoromethyl)arylpyrrole insecticidal and acaricidal agents

Bis- and tris(trifluoromethyl)arylpyrrole compounds which are effective for the control of insects and acarids are described. A method for the insecticidal and acaricidal use of said compounds and methods for the preparation of said compounds are presente