79617-99-5

Basic information

• Product Name: 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride
• Synonyms: Sertraline basis;4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-naphthalenaminehydrochlroide;SERTRALINE RACEMATE HCl;(+)-cis-N-Methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine hyd;Sertraline hydrechloride;4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPHTHALENAMINE HCL;4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE;cis-N-Methyl-4-(3,4-Dichlorophenyl)-tetrahydro-1-naphthalenamineHCl99%MIN.
• CAS NO: 79617-99-5
• Molecular Formula: C₁₇H₁₇Cl₂N*ClH
• Molecular Weight: 342.69
• Product Categories: Pharmaceutical Intermediates
• Mol File: 79617-99-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 275-277°C
• Boiling Point: 443.8 °C at 760 mmHg
• Flash Point: 222.2 °C
• Appearance: /
• CAS DataBase Reference: 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride(79617-99-5)
• EPA Substance Registry System: 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride(79617-99-5)

Safety Data

• Hazardous Substances Data: 79617-99-5(Hazardous Substances Data)

Usage

General Description

The chemical compound 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride, also known as (?)-Cis-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride, is a specific enantiomer of the drug nafadotride, which acts as a selective antagonist for the dopamine receptor D3. It has potential applications in the treatment of various psychiatric and neurological disorders, including drug addiction, depression, and Parkinson's disease. The hydrochloride salt form of this compound is typically used for pharmaceutical purposes, and it is important to handle it with care due to its potential effects on the central nervous system and its toxicity if ingested or inhaled.

Upstream product

• 79836-45-6 trans-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine 

Relevant articles and documents

COMBINATIONS OF ESZOPICLONE AND TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE OR TRANS 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-1-NAPTHALENAMINE, AND METHODS OF TREATMENT OF MENOPAUSE AND MOOD, ANXIETY, AND COGNITIVE DISORDERS

One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders.