79673-53-3Relevant articles and documents
An enantioselective synthesis of α-alkylated pyrroles: Via cooperative isothiourea/palladium catalysis
Rush Scaggs,Scaggs, Toya D.,Snaddon, Thomas N.
supporting information, p. 1787 - 1790 (2019/02/20)
Herein we describe the direct enantioselective Lewis base/Pd catalysed α-allylation of pyrrole acetic acid esters. This provides high isolated yields of highly enantioenriched products and exhibits broad reaction scope with respect to both reaction partners. The products can be readily elaborated in a manner which points towards potential applications in target directed synthesis.
A ONE-STEP CONVERSION OF CERTAIN INDOLE AND PYRROLE GLYOXYLIC ACID ESTERS TO THE CORRESPONDING ACETATES
Demopoulos, Vassilis J.
, p. 2585 - 2594 (2007/10/02)
In this study, a catalytic hydrogen transfer type of hydrogenolysis was developed for the one step conversion of ethyl indole-3-, pyrrole-2- and pyrrole-3-glyoxalates to the corresponding acetates.The structural requirements for this hydrogenolysis were also investigated.
CONTRIBUTION TO THE STUDY OF INDUCTIVE EFFECT TRANSMISSION IN PYRROLE DERIVATIVES
Janda, Miroslav,Srogl, Jan,Holy, Petr,Jakoubkova, Marie
, p. 2404 - 2409 (2007/10/02)
Transmission of the inductive effect in pyrrole derivatives was investigated on 2-ethylpyrrole (VIa), 2-methylpyrrole (VIb), 2-dimethylaminopyrrole (VIc), 2-hydroxymethylpyrrole (VId), methyl 2-pyrrolylacetate (VIe), 2-pyrrolylacetonitrile (VIf), 2-benzenesulfonylmethylpyrrole (VIg) and trimethyl(2-pyrrolylmethyl)ammonium iodide (VIh), by comparison of their relative basicities and acidities.These were determined by IR spectroscopy from the strength of donor-acceptor interactions of the pyrrole derivatives with suitable standard compounds.The found differences show good linear correlations with the ?I substituent constants.On this basis, the transfer of the inductive effect in the given pyrrole series appears to be proportional.