79778-31-7

Basic information

• Product Name: 2-Butenoic acid, 2-(acetylamino)-4-(hydroxymethylphosphinyl)-
• CAS NO: 79778-31-7
• Molecular Formula: C7H12NO5P
• Molecular Weight: 221.15
• Mol File: 79778-31-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Butenoic acid, 2-(acetylamino)-4-(hydroxymethylphosphinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butenoic acid, 2-(acetylamino)-4-(hydroxymethylphosphinyl)-(79778-31-7)
• EPA Substance Registry System: 2-Butenoic acid, 2-(acetylamino)-4-(hydroxymethylphosphinyl)-(79778-31-7)

Safety Data

• Hazardous Substances Data: 79778-31-7(Hazardous Substances Data)

Upstream product

• 60-35-5 acetamide 
• 79778-02-2 4-(hydroxymethylphosphinyl)-2-oxobutanoic acid 

Relevant articles and documents

Enantioselective Synthesis of Both Enantiomers of Phosphinothricin via Asymmetric Hydrogenation of α-Acylamido Acrylates

Both enantiomers of phoshinothricin (1), a naturally occuring amino acid that contains the unique methylphosphinate moiety, were prepared by asymmetric hydrogenation of α-acylamido acrylate precursors 7.L-1 and peptides containing L-1 are inhibitors of the enzyme glutamine synthetase (GS).Inhibition of GS is responsible for the antibiotical and herbicidal properties of these compounds.Synthesis of substrates 7 and parameters influencing the enantioselectivity are discussed.Substrate concentration and solvent polarity appear to have the most marked effects on enantiomeric excesses for a given catalyst system.Enantiomeric excesses reach 91percent for hydrogenations with (R,R)-NORPHOS- and (S,S)-CHIRAPHOS-derived catalysts.