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79784-29-5

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79784-29-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 79784-29-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,7,8 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 79784-29:
(7*7)+(6*9)+(5*7)+(4*8)+(3*4)+(2*2)+(1*9)=195
195 % 10 = 5
So 79784-29-5 is a valid CAS Registry Number.

79784-29-5Relevant articles and documents

4-Aminopiperidine ureas as potent selective agonists of the human β3-Adrenergic receptor

Ashwell, Mark A,Solvibile Jr., William R,Han, Stella,Largis, Elwood,Mulvey, Ruth,Tillet, Jeffrey

, p. 3123 - 3127 (2007/10/03)

The preparation and structure-activity relationships (SARs) of potent agonists of the human β3-adrenergic receptor (AR) derived from a 4-aminopiperidine scaffold are described. Examples combine human β3-AR potency with selectivity over human β1-AR and/or human β2-AR agonism. Compound 29s was identified as a potent (EC50 = 1 nM) and selective (greater than 400-fold over β1- with no β2-AR agonism) full β3-AR agonist with in vivo activity in a transgenic mouse model of thermogenesis.

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